Biomedical Research Training in Drug Abuse

描述：(申请人提供) 此申请要求对机构再提供5年的支持 国家研究服务奖支持多学科博士后 药物滥用(包括尼古丁和烟草依赖)研究方面的培训。我们 请求支持8名博士后研究员(3-4名医学博士，4-5名博士)，用于初级 在以下7个主要领域之一进行培训：(1)系统神经生物学，(2)分子和 细胞机制，(Iii)认知神经科学，(Iv)遗传方法论， (五)遗传流行病学和行为遗传学研究；(六)基因图谱 研究，或(Vii)物质使用障碍的分子遗传学研究。在……里面 除了主要学科的专门化外，还将鼓励学员 要对至少一个其他重点领域有足够的熟悉， 促进在其研究中进行富有成效的跨学科合作 事业。培训计划通常为期3年， 反映了我们申请者群体的不同背景(例如，心理学， 精神病学、内分泌学、数学、经济学、人类学、社会学、 神经科学)，或有相关研究经验的人2年。 对于有经验的药物滥用者，也提供1-2年的博士后奖学金。 在药物滥用研究的新领域寻求培训的研究人员(例如人类 遗传学)。因此，平均每年将招聘3000名新的受训人员(#年为4人 11岁、14岁)。培训计划将强调研究学徒制度。 模型，在一个或多个有经验的人的指导下结合研究 通过授课课程接受更多正式培训的研究导师 个性化教程。该计划的主要优势是可获得性 拥有一支庞大的多学科教员队伍，并积极开展关于 物质使用障碍，代表了许多方面的专业知识 统计/定量、分子和遗传流行病学和神经科学 对物质使用障碍的研究；高效的研究环境 (导师共有60个相关资助研究项目，职业生涯 奖项和科学核心)；主要遗传流行病学的可用性 数据库，以及访问大量正在进行的项目，这些项目提供了许多 为学员提供的研究选择；该计划的地点在全国 领先的医学院，使学员能够利用丰富的 授课课程、研讨会和研究经验；以及悠久的传统 在华盛顿大学成功的指导和研究培训 来自不同知识背景的科学家和内科科学家 物质使用障碍的研究。

DESCRIPTION: (provided by applicant) This application requests a further 5 years of support for an Institutional National Research Service Award to support multi-disciplinary postdoctoral training in drug abuse (including nicotine and tobacco dependence) research. We request support for eight post-doctoral fellows (3-4 MD, 4-5 PhD), for primary training in one of 7 major areas: (i) systems neurobiology, (ii) molecular and cellular mechanisms, (iii) cognitive neuroscience, (iv) genetic methodology, (v) genetic epidemiology and behavioral genetic research, (vi) gene-mapping studies, or (vii) molecular genetic research on substance use disorders. In addition to specialization in a primary discipline, trainees will be encouraged to obtain a sufficient familiarity with at least one other focus area to facilitate fruitful cross-disciplinary collaborations in their research careers. The training program will ordinarily be of 3 years duration, reflecting the diverse background of our applicant pool (e.g. psychology, psychiatry, endocrinology, mathematics, economics, anthropology, sociology, neuroscience), or 2 years for those with pertinent research experience. 1-2-year post-doctoral fellowships are also offered for experienced drug abuse researchers seeking training in a new area of drug abuse research (e.g. human genetics). Thus on average 3 new trainees will be recruited each year (4 in years 11, 14). The training program will emphasize a research apprenticeship model, combining research under the mentorship of one or more experienced research mentors with more formal training through didactic courses or individualized tutorials. Major strengths of the program are the availability of a large multi-disciplinary faculty with an active program of research on substance use disorders, representing expertise in many aspects of statistical/quantitative, molecular and genetic epidemiologic and neuroscience research on substance use disorders; the highly productive research environment (with preceptors having a total of 60 relevant funded research projects, career awards and science cores); the availability of major genetic epidemiologic data-bases, and access to a large number of ongoing projects, that offer many research options to trainees; the program's location in one of the nation's leading medical schools, allowing trainees to take advantage of a rich array of didactic courses and seminars and research experiences; and the long tradition at Washington University of successful mentoring and research training of scientists and physician scientists from diverse intellectual backgrounds for research on substance use disorders.