COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY

本申请的目的是记录 贝勒医学院眼科，参加 作为一个有效和富有成效的临床中心，在拟议的多， 名为“协作性初始青光眼”的中心临床试验 治疗研究（CIGTS）"。 这项研究的目的是评估是否 开角型青光眼的初始治疗更有效， 逐步的医疗方案或通过手术方法。 贝勒 医学院临床中心将参加CIGTS， 确定和招募合格的患者， CIGTS协调中心分配的治疗方案， 在研究操作手册中定义， 保留研究患者，记录研究数据并将其传输至 协调中心，并为将介绍 CIGTS结果。 此应用程序描述了贝勒医学院的能力 临床中心每年入组约24例患者，基于 在为期三个月的试验期间进行的患者资格研究 期 详细介绍了我们的计划，以确定，招聘，遵循 并留住这些病人，我们的意图是获得持续的高- 关于治疗的视觉结果的质量数据，以及人员和 在我们的中心内提供的设施，以执行规定， CIGTS的操作手册。

The intent of this application is to document the ability of the Department of Ophthalmology, Baylor College of Medicine, to participate as an effective and productive clinical center in the proposed multi- center clinical trial entitled "Collaborative Initial Glaucoma Treatment Study (CIGTS)". This study's purpose is to evaluate whether initial treatment of open angle glaucoma is more effective by means of a stepped medical regimen or by means of a surgical approach. Baylor College of Medicine's Clinical Center will participate in the CIGTS by identifying and recruiting eligible patients, administering the treatment regimen as assigned by the CIGTS's coordinating center and defined within the study's Manual of Operations, following and retaining study patients, recording and transferring study data to the Coordinating Center, and contributing to reports that will present the CIGTS results. This application describes the ability of Baylor College of Medicine's Clinical Center to enroll approximately 24 patients per year, based on pilot studies of patient eligibility conducted during a three-month period. Details are provided of our plans to identify, recruit, follow and retain these patients, our intent to obtain consistently high- quality data on the visual outcomes of treatment, and the personnel and facilities available within our center to carry out the provisions of the CIGTS's Manual of Operations.