Mechanical Force and Catalysis

在宏观尺度上产生的任何力都能引起分子尺度上的剧烈变化，甚至破坏共价键。的确，机械力是一种强大的能量来源，它具有扭曲、弯曲和拉伸化学键的能力，在促进化学反应方面是独一无二的。尽管化学家们已经开发出可以通过各种刺激（pH值、光、变构）来控制的催化剂，但迄今为止还很少有机械活化催化剂的例子被报道。该项目旨在创造新型的力活化催化剂。

Any force developed at the macroscopic scale can induce dramatic changes at the molecular scale, even breaking covalent bonds. Indeed, mechanical force is a formidable source of energy that, with its ability to distort, bend and stretch chemical bonds, is unique in the way it promotes chemical reactions. Although chemists have developed catalysts that can be controlled using various stimuli (pH, light, allostery), very few examples of mechanoactivated catalysts have been reported so far. This project aims at creating new types of force-activated catalysts.