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PROSYNDROMAL PEDIATR: FAMILIES ASCERTAINED BY PARENTAL CASES: BIPOLAR DISORDER

PROSYNDROMAL PEDIATR: FAMILIES ASCERTAINED BY PARENTAL CASES: BIPOLAR DISORDER
儿科前综合症：通过父母病例确定的家庭：双向情感障碍
批准号：
6491965
负责人：
ROBERT L FINDLING
金额：
$29.46万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
项目状态：
已结题
起止时间：
2001-09-01 至 2002-08-31
来源：
https://reporter.nih.gov/project-details/6491965
关键词：
biomedical resource computers genetics human tissue immunology inflammation international health /scientific organization lymphatic system parasitism statistics /biometry vaccines virus

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中文摘要
翻译
有研究表明，HLA限制可能会起到重要的作用
英文摘要
It has been suggested that HLA restriction may play a significant role in the development of immunity through vaccine administration. Current efforts focus on the HLA class I alleles and peptide vaccines, and on the prediction of levels of favorable response in 15 ethnic groups, based upon population genetic models and known allele and haplotype frequencies for class I HLA loci. Estimates of coverage probabilities have been obtained based upon these frequencies, and the probable number of alleles needed to achieve such coverage has been obtained based upon individual populations, racial groupings, and all fifteen ethnic groups.
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