SSA Regulation of microglial activity to promote central nervous system homeostasis and limit harmful neuroinflammation
SSA Regulation of microglial activity to promote central nervous system homeostasis and limit harmful neuroinflammation
批准号:
1807879
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2016
资助国家:
英国
项目状态:
已结题
起止时间:
2016 至 --
中文摘要
足够的小胶质细胞活动是必要的,以支持一个健康的中枢神经系统(CNS)环境。作为中枢神经系统的免疫能力细胞,确保小胶质细胞对潜在应激源的反应得到控制以避免潜在的有害神经炎症也很重要。本项目将探索调节小胶质细胞稳态和神经炎症活动的机制,重点是TREM2。
英文摘要
Adequate microglial activity is necessary to support a healthy central nervous system (CNS) environment. As the immune competent cells of the CNS it is also important to ensure microglial responses to potential stressors are controlled to avoid potentially harmful neuroinflammation. This project will explore mechanisms that regulate microglial homeostatic and neuroinflammatory activity with a focus on TREM2.
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