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DETERMINATION OF RATE OF BONE LOSS IN MEN UNDERGOING CASTRATION FOR CANCER

DETERMINATION OF RATE OF BONE LOSS IN MEN UNDERGOING CASTRATION FOR CANCER
因癌症而接受去势的男性骨质流失率的测定
批准号：
6450085
负责人：
JAN M BRUDER
金额：
$23.48万
依托单位：
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-12-01 至 2001-11-30
来源：
https://reporter.nih.gov/project-details/6450085
关键词：
bone density clinical research human subject male male castration neoplasm /cancer surgery pathologic bone resorption prostate neoplasms

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中文摘要
翻译
性腺功能减退导致骨质流失；研究了绝经后女性的骨质流失率，但由于手术或化学阉割而导致性腺功能减退的男性的骨质流失率尚不清楚。本研究旨在评估因前列腺癌而进行手术或药物阉割的男性的骨质流失率。计划接受手术睾丸切除或药物阉割的男性和正常年龄匹配的对照组将被研究。骨密度测量将在基线、6个月和12个月时测定。
英文摘要
Hypogonadism results in a high turnover bone loss; the rate of bone loss in women after menopause has been studied, but the rate of bone loss in men with hypogonadism due to surgical or chemical castration is unknown. This study is designed to assess the rate of bone loss in men immediately following surgical or medical castration because of prostate cancer. Men who are scheduled to undergo surgical orchietomy or medical castration and normal age-matched controls will be studied. Bone mineral density measurements will be determined at baseline, 6 and 12 months.
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会议论文
GENETICS OF BONE DENSITY IN MEXICAN AMERICANS - CONTINUATION
GENETICS OF BONE DENSITY IN MEXICAN AMERICANS - CONTINUATION
PREVENTION OF BONE LOSS WITH ALENDRONATE IN PROSTATE CANCER WITH HORMONE DEPRIVA
GENETICS OF BONE DENSITY IN MEXICAN AMERICANS - CONTINUATION
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