Development of B(MIDA)-based directing groups for C-H functionalization

使用B(MIDA)衍生物等受保护的硼酸衍生物的实际优势将被扩大，以允许它们用作过渡金属催化的芳基-B(OH)2衍生物的C-H官能化邻位以及烯基-Csp2和烷基-Csp3官能化的官能化基团。鉴于这些功能的广泛商业化，我们预计这些新的定向B(MIDA)衍生物的成功展示将对化学工业，包括制药、农用化学品和材料工业具有重要意义。

The practical advantages of using 'protected' boronic acid derivatives such as B(MIDA) derivatives will be expanded to permit their use as functional directing groups for transition metal catalyzed C-H functionalization ortho of aryl-B(OH)2 derivatives as well as for alkenyl-Csp2 and alkyl-Csp3 functionalizaiton. Givent he wide spread commercialization of these functionalities, we expect that a successful demonstration of these new directing B(MIDA) derivatives will be of importance to chemical industries, including the pharmaceutical, agrochemical, and material industries.