Behavioral Genetic Study of Religiosity and Alcoholism

描述（由申请人提供）：虽然宗教和精神有 一直被认为影响了广泛的人类经验， 对这一现象的科学研究没有跟上日益增长的 它与健康、医疗和酗酒问题相关的证据。 这 申请寻求小额赠款支持（R 03），用于二次分析， 数据来自三个大规模的NIAAA支持的孪生项目，涉及青少年 双胞胎和成年双胞胎 有了这些数据，我们可以详细说明最近的行为- 基因研究结果，有宗教和 酗酒;特别是宗教如何影响传播， 酒精中毒在几代人中的发展。 具体目标是：（1） 研究宗教与那些被认为 是酗酒的遗传前兆，宗教和酗酒之间 变量本身;（2）检查宗教可以发挥的调节作用， 酒精中毒家族史对后代酒精中毒的影响 和其他负面结果，以及（3）进行初步审查 与未来研究方向有关的问题，包括（a）多层面 宗教性的本质;（B）宗教性与其他宗教性的关系 个体差异变量;（c）宗教信仰与其他模型的关系 （d）考虑发展问题（每一个 数据集采用队列序贯设计）， 宗教对酒精中毒和其他疾病的发展和过程。

DESCRIPTION (provided by applicant): Although religion and spirituality have always been thought to influence a wide range of human experience, the scientific study of this phenomenon has not kept pace with the growing evidence of its relevance to health, medical, and alcoholism concerns. This application seeks small grant support (R03) for secondary analyses involving data from three large-scale NIAAA-supported twin projects involving adolescent twins and adult twins. Given these data, we can elaborate on recent behavioral- genetic findings that have bearing on the relationship between religion and alcoholism; in particular how religion can impact the transmission and development of alcoholism across generations. The specific aims are: (1) to examine interaction of effects between religion and those variables thought to be genetic precursors to alcoholism and between religion and alcoholism variables per se; (2) to examine the moderating role that religion can play in qualifying the impact of family history of alcoholism on offspring alcoholism and other negative outcomes, and (3) to conduct preliminary examinations relevant to future research directions including (a) the multidimensional nature of religiosity; (b) the relationship between religiosity and other individual difference variables;(c) how religiosity is related to other models of alcoholism etiology; and (d) consideration of developmental issues (each data set utilizes a cohort sequential design) regarding the moderating role of religiosity on development and course of alcoholism and other disorders.