HYDROGEN BOND MEDIATED NUCLEIC ACID BASE INTERACTIONS

核酸碱基相互氢键的文库 都是使用纯几何约束进行计算的。图书馆 也计算了单一氨基酸的氢键 核酸碱基。这些库对于个人来说太大了 来浏览，所以我编写了一个指向这些库的接口。我 我选择了使用MDLI的Chime插件的Web界面和 Netscape Navigator显示三维分子模型。这个 界面允许用户浏览该库并识别 已知PDB结构文件中的氢键相互作用。电脑 图形实验室的资源已用于检索PDB文件和 使用MidasPlus显示结构文件。MidasPlus还 用于重叠库中的元素，以了解c1‘如何绑定 各种氢键结构之间的重叠。

Libraries of nucleic acid bases hydrogen bonding to each other have been calculated using purely geometric constraints. Libraries have also been calculated for single amino acids hydrogen bonding with nucleic acid bases. These libraries are too large for an individual to browse through, so I am writing an interface to these libraries. I have chosen a web-interface using the Chime plugin from MDLI and Netscape Navigator to display 3-dimensional molecular models. The interface allows users to browse through the library and to identify hydrogen bond interactions in known pdb structure files. Computer Graphics Laboratory resources have been used to retrieve pdb files and to display the structure files using MidasPlus. MidasPlus has also been used to overlap elements from the libraries to see how C1' bonds overlap between various hydrogen bonded structures.