Effects of antibiotics, vaccines and environment on the population biology of bacterial respiratory pathogens in Australian Indigenous children – a synthesis of studies

20多年来，北领地的研究人员一直在研究严重影响土著儿童的中耳和下呼吸道感染。项目包括抗生素和疫苗干预，但发病率仍然很高。关于引起这些感染的细菌和干预措施的影响，人们已经了解了很多。这项研究将综合这些发现，并探索环境影响，以进一步提供预防和治疗策略。

For over 20 years researchers in the Northern Territory have studied middle ear and lower respiratory infections which severely affect Indigenous children. Projects have included antibiotic and vaccine interventions, however disease rates remain high. Much has been learned about the bacteria causing these infections and the effects of interventions. This study will synthesise these findings, and explore environmental influences, to further inform prevention and treatment strategies.