Immunobiology of Blood and Vascular Systems Training

描述（由申请人提供）： 此应用程序请求支持跨学科的培训计划， 范德比尔特血液和血管系统免疫生物学领域 大学医学中心和Meharry医学院。IBVS培训 计划（IBVSTP）专注于炎症和免疫的分子方面 介导人类血液和血管疾病。33名教师 来自范德比尔特的微生物学和免疫学系，细胞 生物学，分子生理学和生物物理学，医学，神经学，病理学， 药理学和外科医生3（移植中心）将与教师接口 来自Meharry的微生物学，免疫学和遗传学系， 实施IBVS培训计划。大量的证据表明， 富有成效的合作，这些教师导师构成了一个高度 在分子生物学领域具有互补研究兴趣的互动团队 影响健康和疾病中的血液和血管系统的机制。 他们重叠的研究领域包括（1）功能基因组学和 炎症蛋白质组学，（2）先天免疫和炎症，（3）抗原 加工和呈递，（4）淋巴细胞信号传导和基因表达，（5） 逆转录病毒和免疫系统之间的功能相互作用，（6） 淋巴细胞的发育和分化;（7）抗原受体的产生 多样性，（8）自身免疫和移植排斥，（9）发育 心血管系统的生物学和遗传学，和（10）细胞成像， 肽/蛋白转导和亚细胞靶向。 为了支持这些方面的创新培训，应用程序要求 支持6名博士前培训生，6名博士后培训生，以及 本科生。被范德比尔特录取的博士前实习生 跨学科研究生课程（IGP）或梅哈里医学院将是 有资格获得IBVS培训计划的支持， IBVS培训计划指导委员会的研究生课程。 持有博士学位的博士后研究生和/或医学博士学位将被任命 等待参与导师的提名和IBVS的决定 培训计划指导委员会。帮助培养下一代 年轻的生物医学科学家，合格的本科生将被选中 作为IBVS培训计划的学员参加夏季研究计划。 IBVS培训计划的所有学员都将参加 结构化的教学课程，包括关于“功能基因组学”的新课程 和血液和血管系统的蛋白质组学”，每周研究进展 研讨会系列，以及由参与IBVS培训计划的 教师

DESCRIPTION (provided by applicant): This application requests support for an interdisciplinary training program in the field of Immunobiology of Blood and Vascular Systems at Vanderbilt University Medical Center and Meharry Medical College. The IBVS Training Program (IBVSTP) is focused on molecular aspects of inflammation and immunity that mediate human blood and vascular disorders. Thirty-three faculty preceptors from Vanderbilt's Departments of Microbiology and Immunology, Cell Biology, Molecular Physiology and Biophysics, Medicine, Neurology, Pathology, Pharmacology, and Surger3 (Transplant Center) will interface with faculty from Meharry's Department of Microbiology, Immunology, and Genetics to implement the IBVS Training Program. As evidenced by a significant number of fruitful collaborations these faculty preceptors constitute a highly interactive team with complementary research interests in the molecular mechanisms affecting the blood and vascular system in health and disease. Their overlapping research fronts encompass (1) functional genomics and proteomics of inflammation, (2) innate immunity and inflammation, (3) antigen processing and presentation, (4) lymphocyte signaling and gene expression, (5) functional interplay between retroviruses and the immune system, (6) lymphocyte development and differentiation, (7) generation of antigen receptor diversity, (8) autoimmunity and transplant rejection, (9) developmental biology and genetics of cardiovascular system, and (10) cell imaging, peptide/protein transduction, and subcellular targeting. To support innovative training in these fronts, the application requests support for 6 pre-doctoral trainees, 6 post-doctoral trainees, and undergraduate students. Predoctoral trainees accepted by the Vanderbilt Interdisciplinary Graduate Program (IGP) or Meharry Medical College will be eligible for IBVS Training Program support pending evaluation of their first year of graduate studies by the IBVS Training Program Steering Committee. Postdoctoral trainees holding Ph.D. and/or M.D. degrees will be appointed pending nomination by a participating preceptor and the decision of the IBVS Training Program Steering Committee. To help foster the next generation of young biomedical scientists, qualified undergraduate students will be selected to participate as IBVS Training Program trainees in a summer research program. All trainees in the IBVS Training Program will be expected to participate in structured didactic offerings, including a new course on "Functional Genomics and Proteomics of Blood and Vascular Systems", a weekly Research-In-Progress seminar series, and a journal club led by participating IBVS Training Program faculty preceptors.