Understanding interactions between meta-cognition and social behaviour in a psychosis prone population

本研究拟探讨精神病患者元认知缺陷的具体因果机制，探讨这些缺陷是否会导致真实的世界结果，探讨在心理测量学分型得分较高的神经型人群中是否存在病理不确定性，研究精神病患者的情绪是否与元认知缺陷相互作用。该项目建立在“元认知”和“自我”的概念基础上，本研究的预期结果包括对精神分裂症患者的整体元认知和元认知缺陷背后的机制的深入理解。这有可能解释文献中的巨大异质性，包括不同的治疗反应。这项拟议中的研究将解开情绪对社会认知（准确性）和元认知（信心）的影响，目前这些影响存在相互矛盾的证据。最后，纳入HMDVR将促进新的和更准确的进展跟踪（评估）和缓解警告（预防）程序，以及VR作为精神分裂症元认知缺陷的潜在治疗（干预）。

This project proposes to 1) investigate the specific causal mechanisms of metacognitive deficits in individuals with psychosis 2) ask whether these deficits lead to real world outcomes 3) investigate whether pathological uncertainty is seen in the neurotypical population scoring highly on psychometric schizotypy 4) investigate whether emotion interacts with metacognitive deficits in psychosis.The project builds on the concepts of 'metacognition' and 'self-reflectivity'.Head Mounted Display (HMD) Virtual Reality (VR) will be used.Anticipated outcomes for this study includes a developed understanding of the mechanisms behind both global metacognition and metacognitive deficits in schizophrenia. This has the potential to explain the vast heterogeneity in the literature including divergent treatment responses. The proposed study will disentangle the effects of emotion on social cognition (accuracy) and metacognition (confidence), which currently holds conflicting evidence. Finally, the inclusion of HMDVR will promote both novel and more accurate progress tracking (assessment) and remission warning (prevention) procedures, and VR as a potential therapy of metacognitive deficits in schizophrenia (intervention).