Core--Research development

建议设立的内森老龄问题休克中心有四个目的：(1)提高老龄基础生物学研究的质量，(2)促进老龄研究的协调，(3)创建区域/国家资源，以及(4)为老龄研究中的教师成长创造环境。研究开发中心为教师成长创造的环境也将提高老龄化基础生物学的研究质量。研究开发中心为教师成长创造的环境也将提高老龄化基础生物学的研究质量。研究开发的一个主要重点将是促进核心提供的技术的整合，以便在选定的模型系统中开展细胞衰老和死亡的细胞和分子基础研究。利用这些核心的研究项目将能够发现与衰老相关的基因，定位其基因产物，描述其表型，并确定基因产物的功能。这一整合将通过一系列活动来实现：(1)严格选择试点项目的支持申请，(2)严格挑选教员，批准有限的工资支持试点项目，(3)由资深教员为初级教员和其他新入门的教师提供正式的指导计划，(4)创建关于衰老生物学的研讨会课程，以及(5)开展客座演讲者和务虚会计划，以防止关于衰老生物学的发现。试点项目支持申请的选择和有限工资支持的教师选择将由一个资深教师委员会负责。所有这些活动都旨在创造一个互动、合作但严格的环境，在这种环境中，智力的发酵将导致招聘新的教员来研究衰老的细胞和分子生物学，并为他们提供出色的设施，以支持优秀教员进行高质量的研究。

The proposed Nathan Shock Center on Aging as a four-fold purpose: (1) To enhance the quality of research in the basic biology of aging, (2) to facilitate coordination of research on aging, (3) to create a regional/national resource and (4) to create an environment for faculty growth in aging research. The creation of an environment for faculty growth by the Research Development Core also will enhance the quality of research in the basic biology of aging. The creation of an environment for faculty growth by the Research Development Core also will enhance the quality of research in the basic biology of aging. A major focus of the Research Development will be to promote the integration of the technologies offered by the Core so to develop research in the cellular and molecular basis of cell senescence and death in selected model systems. Research programs utilizing the Cores will be able to discover aging- related genes, localize their gene products, describe their phenotype and determine the function of the gene products. This integration will be created by a series of activities: (1) Rigorous selection of applications for the support of Pilot Projects, (2) rigorous selection of faculty with approved Pilot Projects for limited salary support, (3) a formal program of mentoring junior faculty and others new to th4e biology of aging by senior faculty (4) creation of a seminar course in the biology of aging and (5) mounting a program of guest speakers and retreats for prevention of findings on the biology of aging. The selection of applications for support of Pilot Projects and the selection of faculty for limited salary support will be by a committee of senior faculty. All these activities are designed to create an interactive and collegial but rigorous environment in which the intellectual ferment would lead to recruitment of new faculty to research in the cell and molecular biology of aging and provide them with outstanding facilities to support the production of high quality research by outstanding faculty.