Effects of replacement and withdrawal of testosterone in human males on muscle, bone and fat

男性性激素或雄激素缺乏症（AD）是一种常见但诊断不足的疾病。阿尔茨海默病会降低幸福感，导致肌肉无力、骨骼脆弱和体重增加。尖端技术将用于帮助解释AD与这些负面影响，特别是对肌肉功能的影响之间的关系。鉴于衰老、虚弱、骨质疏松和肥胖的重要性，了解激素在这些疾病中的作用可能对预防和治疗具有重要意义。

Male sex hormone or androgen deficiency (AD) is a common, but under-diagnosed condition. AD decreases well being and contributes to muscle weakness, bone fragility and weight gain. Cutting edge technology will be used to help explain how AD may relate to these negative effects, particularly on muscle function. Given the importance of aging, frailty, osteoporosis and obesity, understanding the role of hormones in these conditions may have major implications for prevention and treatment.