IN VIVO MICROSCOPY TECHNOLOGIES & APPLICATIONS: MICRO PET & MICRO CT
IN VIVO MICROSCOPY TECHNOLOGIES & APPLICATIONS: MICRO PET & MICRO CT
批准号:
6493760
负责人:
ELAINE G FITZSIMONS
金额:
$28.8万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-09-01 至 2002-08-31
中文摘要
在MR显微镜的帮助下,长胡子的蝙蝠,翼手蝙蝠
Parnellii,已被证明有正常的放大(积水)
耳蜗的某些区域(Scala媒体)。这些放大
发生在与特定领域相关的非常尖锐的调谐。这很重要
以确定这是否是所有耳蜗所共有的形态特征
在最敏感的地区。同样重要的是确定
如果这主要与高频有关,并解决
关于它们之间是否存在形态差异的问题
专门用于高频听力和低频听力的动物。目的
这项研究的目的是获得高分辨率图像,这将使
美国在几种小型哺乳动物身上重建了鳞片。至
为此,我们建议使用两种啮齿动物(沙鼠、豚鼠)
频率敏感度和听力能力都有很好的记录。在……里面
除了翼手龙,我们将使用蝙蝠Eptesicus fuscus,它的
听力与长胡子的蝙蝠有很大的不同。
英文摘要
With the aid of MR microscopy, the mustached bat, pteronotus
parnellii, has been shown to have normal enlargements (hydrops) in
certain regions of the cochlea (scala media). These enlargements
occur in specific areas related to very sharp tuning. It is important
to determine if this is a morphological feature common to all cochleas
in regions of greatest sensitivity. It is also important to determine
if this is related primarily to high frequencies and to address the
question as to whether there are morphological differences among
animals specialized for high vs. low frequency hearing. The purpose
of this research is to obtain high resolution images which will allow
us to reconstruct the scalae in several species of small mammals. To
do this we propose to use two rodents (gerbils, guinea pigs) whose
frequency sensitivity and hearing capacities are well documented. In
addition to pteronotus, we will use the bat Eptesicus fuscus whose
hearing capacities are very different from those of the mustached bat.
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会议论文
MR MICROSCOPY EXHIBIT AT NATL MUSEUM OF HEALTH & MED: 3 D IMAGING
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批准号:6493764
-
项目类别:
-
资助金额:$28.8万
-
财政年份:2001
-
负责人:ELAINE G FITZSIMONS
-
依托单位:
IN VIVO MICROSCOPY TECHNOLOGIES & APPLICATIONS: MICRO PET & MICRO CT
-
批准号:6348193
-
项目类别:
-
资助金额:$1.5万
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财政年份:2000
-
负责人:ELAINE G FITZSIMONS
-
依托单位:
MR MICROSCOPY EXHIBIT AT NATL MUSEUM OF HEALTH & MED: 3 D IMAGING
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批准号:6348197
-
项目类别:
-
资助金额:$0.75万
-
财政年份:2000
-
负责人:ELAINE G FITZSIMONS
-
依托单位:
MR MICROSCOPY EXHIBIT AT NATL MUSEUM OF HEALTH & MED: 3 D IMAGING
-
批准号:6220754
-
项目类别:
-
资助金额:$0.75万
-
财政年份:1999
-
负责人:ELAINE G FITZSIMONS
-
依托单位:
IN VIVO MICROSCOPY TECHNOLOGIES & APPLICATIONS: MICRO PET & MICRO CT
-
批准号:6220750
-
项目类别:
-
资助金额:$1.5万
-
财政年份:1999
-
负责人:ELAINE G FITZSIMONS
-
依托单位:
海外基金