ESTABLISH OF POST CHERNOBYL NIS THYROID BANKS

描述：(申请人描述) 该项目将形成一个国际支持的合作研究 为许多致力于甲状腺癌问题的团体提供资源，这些团体有 在切尔诺贝利事故之后。它旨在促进协作和 避免在使用有限的和非常有价值的资源方面的竞争。四个 参与该项目的资助组织是美国国立卫生研究院 美国卫生局、欧盟委员会、世界卫生组织和 日本佐佐川纪念健康基金会。该项目的基础是 一种从甲状腺病例中收集组织的协作方法 切尔诺贝利周围地区的癌症与同步采血 样本和基本临床信息。该项目有几个目标：(A) 确保向患者提供尽可能最佳的诊断服务，(B) 提供国际公认的病理学家同意的诊断。这 诊断将提供给来自这些国家的研究小组 开展分子生物学、治疗学、流行病学等 学习。(C)确保甲状腺癌标本适当 描述和抽样，并且材料可用于适当的 研究研究(冰冻组织、固定组织切片、提取的DNA/RNA和 血样连同相关信息)，通过商定的议定书 由相关的研究机构提供。该项目将提供一个有价值的 为未来对辐射机制感兴趣的研究人员提供研究工具 放射治疗后甲状腺肿瘤的发生。

DESCRIPTION: (Applicant's Description) This project will form an internationally supported collaborative research resource for many groups working on the problems of thyroid cancer which has followed the Chernobyl accident. It is designed to promote collaboration and avoid competition in the use of limited and very valued resources. The four funding organizations involved in the project are the National Institute of Health of the USA, the European Commission, the World Health Organization and the Sasakawa Memorial Health Foundation of Japan. The basis of the project is a collaborative approach to the collection of the tissue from cases of thyroid cancer in the areas around Chernobyl with simultaneous collection of blood samples and basic clinical information. The project has several aims (a) to ensure that the best possible diagnostic service is given to patients, (b) to provide a diagnosis agreed by internationally recognized pathologists. This diagnosis will be made available to research groups from those countries carrying out molecular biological, therapeutic, epidemiological and other studies. (c) to ensure that specimens of thyroid cancer are properly described and sampled, and that materials are available for appropriate research studies (frozen tissue, fixed tissue sections, extracted DNA/RNA and blood samples, together with relevant information), through a protocol agreed by the research organizations involved. The project will provide a valuable research tool for future researchers interested in the mechanism of radiation tumourigenesis of the thyroid following irradiation.