NEUROBIOLOGY OF MILD COGNITIVE IMPAIRMENT IN THE ELDERLY

名为“轻度认知障碍的神经生物学”的项目 老年人的损伤”汇集了一些基础科学家 以及来自芝加哥和其他大学的临床科学家。 的 该项目将设在拉什长老会-圣卢克医疗中心 在芝加哥。 该计划项目包括一个行政核心 具有临床/组织分布组件和统计数据， 数据管理核心。 此外，以下四项研究 项目完成程序：1）Tau异常和轻度 老年人的认知障碍（John Trojanowski，University of 宾夕法尼亚州，项目负责人）; 2）脑卒中相关神经病理学和 老年人的轻度认知障碍（Dennis Dickson，Albert 爱因斯坦医学院，项目负责人）; 3）胆碱能基础 前脑神经营养缺失与轻度认知功能障碍 （项目负责人Elliott Mufson）;以及Synaptic 老年痴呆症和轻度认知障碍（Steven DeKosky，匹兹堡大学，项目1负责人）。 每个核心将 支持所有这些研究项目。 此外，这些项目将 从NIA资助的Rush接收临床数据和组织样本 ADC宗教秩序研究核心和神经病理学核心 所有项目。

The Program Project entitled "Neurobiology of Mild Cognitive Impairment in the Elderly" brings together a number of basic scientists and clinician scientists from Chicago and outside universities. The project will be based at Rush Presbyterian-St. Luke's Medical Center in Chicago. The Program Project consists of an Administrative Core with a Clinical/Tissue Distribution component and a Statistics and Data Management Core. In addition the following four research projects complete the program: 1) Tau abnormalities and Mild Cognitive Impairment in the Elderly (John Trojanowski, University of Pennsylvania, project leader); 2) Age-Related Neuropathology and Mild Cognitive Impairment in the Elderly (Dennis Dickson, Albert Einstein College of Medicine, project leader); 3) Cholinergic Basal Forebrain Neurotrophic Abnormalities and Mild Cognitive Impairment in the Elderly (Elliott Mufson, Project Leader); and Synaptic Abnormalities and Mild Cognitive Impairment in the Elderly (Steven DeKosky, University of Pittsburgh, project 1Leader). Each core will support all of these research projects. Moreover, these projects will receive clincial data and tissue samples from the NIA funded Rush ADC Religious Orders Study Core and the Neuropathology Core for all projects.