CRANIOFACIAL COMPLEMENTARY & ALTERNATIVE MEDICINE CENTER

该提案建立俄勒冈州颅面疾病补充和替代医学研究中心（OCCAM）。OCCAM将开发必要的资源，对辅助和替代医学（CAM）方法进行严格的科学调查，以诊断和管理颅面疾病（CFD）。OCCAM将设在凯撒永久健康研究中心。通过OCCAM，俄勒冈东方医学院（COCM）、国家自然医学学院（NCNM）、西部各州脊椎指压牙科（SoD）和临床研究中心（CRC）以及Kaiser Permanente西北分部（KPNW）——所有这些都位于波特兰——将合作开展关于潜在疗效、有效性、可接受性、对卫生保健资源利用的影响的研究。与cfd的辅助医学做法有关的社会心理和其他健康结果，以及其中一些做法背后的生理和心理机制。此外，该中心将使我们能够培训和指导对开发CAM应用感兴趣的年轻研究人员进行三个II期临床试验：TMD疼痛管理的补充医学方法；TMD女性患者的替代医学治疗牙周炎的补充自然疗法。为了支持这些项目和OCCAM，我们提出了四个核心小组：行政核心、生物统计学和经济学核心、测量和依从性核心以及实验室核心。通过提议的管理策略和外部咨询委员会，OCCAM将在传统和CAM社区之间提供独特的研究合作，以解决有关CFD预防、诊断和治疗的许多重要问题。重要的是，OCCAM和参与机构致力于这些合作努力，并在本提案所要求的资金之外带来额外的机构承诺。

This proposal establishes the Oregon Center for Complementary and Alternative Medicine Research in Craniofacial Disorders (OCCAM). OCCAM will develop the resources necessary for rigorous scientific investigation of complementary and alternative medicine (CAM) approaches to diagnosing and managing craniofacial disorders (CFD). OCCAM will be based at the Kaiser Permanente Center for Health Research. Through OCCAM, the Oregon College of Oriental Medicine (COCM), National College of Naturopathic Medicine (NCNM), Western States Chiropractic Dentistry (SoD) and Clinical Research Center (CRC), and Kaiser Permanente Northwest Division (KPNW)-all of which are based in Portland-will collaborate to conduct research on the potential efficacy, effectiveness, acceptability, effects on health care resource use, and psychosocial and other health outcomes associated with CAM practices for CFDs as well as the physiological and psychological mechanisms underlying some of these practices. Further, this center will enable us to train and mentor young investigators who are interested in developing a CAM application are three Phase II clinical trials: Complementary Medicine Approaches to TMD Pain Management; Alternative Medicine Approaches Among Women with TMD; and Complementary Naturopathic Medicine for Periodontitis. To provide support for these projects and for OCCAM, we propose four core groups: the Administrative Core, the Biostatistics and Economics ore, the Measurement and Adherence Core, and the Laboratory Core. With the propose management strategy and external Advisory Committee, the OCCAM will provide a unique research collaboration between conventional and CAM communities to address many important questions about CFD prevention, diagnosis, and treatment. Importantly, OCCAM and the participating institutions are committed to these collaborative efforts and bring additional institutional commitment beyond the funds requested in this proposal.