CORE--GENETIC TOXICOLOGY RESEARCH FACILITY
CORE--GENETIC TOXICOLOGY RESEARCH FACILITY
批准号:
6495681
负责人:
Joanna Louise Groden
金额:
$7.35万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-04-01 至 2002-03-31
中文摘要
本研究核心的目标是研究分子
遗传毒性环境因子代谢的机制,
有毒中间体;遗传毒性剂如何损害DNA; DNA损伤如何导致
突变;一些细胞反应如何防止诱变
(e.g., DNA修复和细胞周期停滞)。 据说,这些目标中的每一个都
符合中心的目标作为一个整体,因为它们可以相关
关于“遗传多样性对个人对下列问题的反应的影响:
有毒的环境因子"
英文摘要
The goals of this Research Core are to investigate the molecular
mechanisms by which genotoxic environmental agents are metabolized to
toxic intermediates; how genotoxic agents damage DNA; how DNA damage leads
to mutation; how some cellular responses function to prevent mutagenesis
(e.g., DNA repair and cell cycle arrest). Each of these aims is said to
fit within the goals of the center as a whole in that they can be related
to the "impact of genetic diversity on the response of the individual to
toxic environmental agents."
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Modernization and Expansion of the University of Illinois at Chicago Animal-Based Research Program
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批准号:10374588
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项目类别:
-
资助金额:$674.91万
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财政年份:2021
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负责人:Joanna Louise Groden
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依托单位:
Functions of the BLM Helicase in Telomere Maintenance
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批准号:7617657
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项目类别:
-
资助金额:$31.13万
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财政年份:2008
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负责人:Joanna Louise Groden
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依托单位:
Functions of the BLM Helicase in Telomere Maintenance
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批准号:8228150
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项目类别:
-
资助金额:$30.19万
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财政年份:2008
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负责人:Joanna Louise Groden
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依托单位:
Functions of the BLM Helicase in Telomere Maintenance
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批准号:7474314
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项目类别:
-
资助金额:$31.13万
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财政年份:2008
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负责人:Joanna Louise Groden
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依托单位:
Functions of the BLM Helicase in Telomere Maintenance
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批准号:8024482
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项目类别:
-
资助金额:$30.19万
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财政年份:2008
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负责人:Joanna Louise Groden
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依托单位:
Functions of the BLM Helicase in Telomere Maintenance
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批准号:7777778
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项目类别:
-
资助金额:$31.13万
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财政年份:2008
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负责人:Joanna Louise Groden
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依托单位:
Integrative Training in Biomedical Systems
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批准号:8688260
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项目类别:
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资助金额:$23.86万
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财政年份:2005
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负责人:Joanna Louise Groden
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依托单位:
Integrative Training in Biomedical Systems
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批准号:8869008
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项目类别:
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资助金额:$24.14万
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财政年份:2005
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负责人:Joanna Louise Groden
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依托单位:
Integrative Training in Biomedical Systems
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批准号:9303843
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项目类别:
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资助金额:$6.73万
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财政年份:2005
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负责人:Joanna Louise Groden
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依托单位:
Integrative Training in Biomedical Systems
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批准号:8474494
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项目类别:
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资助金额:$11.78万
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财政年份:2005
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负责人:Joanna Louise Groden
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依托单位:
Core--DNA Laboratory
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批准号:6617330
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项目类别:
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资助金额:$19.7万
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财政年份:2002
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负责人:Joanna Louise Groden
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依托单位:
Core--DNA Laboratory
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批准号:6579912
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项目类别:
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资助金额:$19.7万
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财政年份:2002
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负责人:Joanna Louise Groden
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依托单位:
Core--DNA Laboratory
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批准号:6618911
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项目类别:
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资助金额:$19.7万
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财政年份:2002
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负责人:Joanna Louise Groden
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依托单位:
CORE--GENETIC TOXICOLOGY RESEARCH FACILITY
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批准号:6449001
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项目类别:
-
资助金额:$16.52万
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财政年份:2001
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负责人:Joanna Louise Groden
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依托单位:
CORE--GENETIC TOXICOLOGY RESEARCH FACILITY
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批准号:6367990
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项目类别:
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资助金额:$15.66万
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财政年份:2000
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负责人:Joanna Louise Groden
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依托单位:
Mouse Models of Gastrointestinal Cancer
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批准号:6729247
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项目类别:
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资助金额:$85.0万
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财政年份:1999
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负责人:Joanna Louise Groden
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依托单位:
Mouse Models of Gastrointestinal Cancer
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批准号:6950443
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项目类别:
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资助金额:$26.8万
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财政年份:1999
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负责人:Joanna Louise Groden
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依托单位:
CORE--GENETIC TOXICOLOGY RESEARCH FACILITY
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批准号:6106359
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项目类别:
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资助金额:$15.66万
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财政年份:1999
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负责人:Joanna Louise Groden
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依托单位:
MOUSE MODELS OF GASTROINTESTINAL CANCER
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批准号:6175340
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项目类别:
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资助金额:$55.39万
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财政年份:1999
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负责人:Joanna Louise Groden
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依托单位:
MOUSE MODELS OF GASTROINTESTINAL CANCER
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批准号:6377681
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项目类别:
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资助金额:$60.13万
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财政年份:1999
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负责人:Joanna Louise Groden
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依托单位:
海外基金