Radiation Field Modeling/Computerized Treatment Planning

近年来，医学成像和定位技术的巨大进步对物理和计算机技术提出了挑战，以扩展计算机治疗计划和优化的能力。当前和最终版本已经过验证，可在Windows NT/2000平台上临床使用。Windows NT版本现在是标准的临床治疗计划平台，Macintosh平台将停止使用。NT版本基于OpenGL图形引擎，它提供了卓越的3D图像显示和操作。提出了一种基于实时体绘制的交互式图像融合算法。虽然这目前用于CT和MRI图像，但任何图像集都可以融合。为了与劳伦斯利弗莫尔国家实验室通信，实现了RTOG格式的文件/图像导入和导出。DICOM-RT格式的导入和导出将在2001财年实施，以便与与CIT合作的Telesynergy放射成像工作站项目进行通信。与LLNL的通信允许使用其PEREGRINE蒙特卡洛剂量计算引擎进行临床研究项目。该引擎还将用于验证NIH-TPS的光子剂量计算方法。还计划将TPS用于立体定向放射外科/放疗（SRS/SRT）以及强度调制放疗（IMRT）。一个单独的近距离治疗程序已经开发出来，它使用AAPM TG-43形式进行计算。修改了角度和径向剂量函数，以允许血管内近距离治疗的治疗计划。我们正在就CRADA进行谈判，以进一步开发该系统，包括剂量优化和结合实时体积绘制技术。

The vast improvements of the medical imaging and localization technology over recent years has brought a challenge to physics and computer technology to extend the capabilities of computerized treatment planning and optimization. The current and final release has been validated for clinical use on Windows NT/2000 platforms. The Windows NT version is now the standard clinical treatment planning platform and the Macintosh platform will be discontinued. The NT version is based on the OpenGL graphics engine, which provides superior 3D image display and manipulation. A new interactive algorithm has been developed for image fusion using real-time volume rendering. Although this is currently used with CT and MRI images, any image set can be fused. File/image import and export in RTOG format has been implemented for communication with Lawerence Livermore National Laboratory. Import and export in DICOM-RT format will be implemented in FY-2001 for communication with the Telesynergy Radiological Imaging Workstation Project in conjunction with CIT. Communication with LLNL permits a clinical research project using their PEREGRINE Monte Carlo dose calculation engine. This engine will also be used to validate the photon dose calculation methodology of the NIH-TPS. Also planned is the use of the TPS for stereotactic radiosurgery/radiotherapy (SRS/SRT) as well as Intensity Modullated Radiotherapy (IMRT). A separate program for brachytherapy has been developed, which performs calculations using the AAPM TG-43 formalism. Modifications to the angular and radial dose functions have been made to permit treatment planning for intravascular brachytherapy. We are in the process of negoating a CRADA for further development of the system, including dose optimization and incorporating real-time volume rendering technology.