Integrating Multi-Assessment Protocols into Practice

描述：(申请人提供) 国家在药物滥用治疗领域的领导地位已经认识到有必要 建立有效的治疗方法，并将这些治疗方法推广到更多人 寻求治疗。这一点反映在NIDA诊所的建立上 通过大规模临床试验研究有效性的试验网络(CTN) 试验，并建立CSAT实践研究协作组 (PRCs)在研究和实践之间架起桥梁。这些项目的全部承诺 然而，除非有示范的干预措施，否则努力是无法实现的。 有效性被应用到临床实践中。尽管有可用的文献 组织变革的影响因素、影响因素述评 采用治疗创新，以及研究和实践之间的差距， 没有系统的努力来整合这些文献，开发 测量策略，并使用这些测量方法，研究干预采用 在多点临床试验中。 这是一项关于制定和应用多级评估协议(MAP)的建议 调查行为导向药物滥用治疗的程度 以社区为基础的提供者参与的干预措施 多点临床试验。拟议的项目将建立以下程序 调查#年采用基于研究的治疗干预措施的情况 治疗领域，确定采用干预措施的障碍，并确定 增加或减少收养可能性的因素。我们将发展和 在甲基苯丙胺的背景下实地测试MAP战略 多点临床试验，这不是NIDA CTN的一部分。到时候我们会的 将地图应用于CTN激励强化疗法/激励 采访目前处于萌芽阶段的临床试验。长期计划 目标是制定战略，供国家CTN使用，这将 增加采用临床试验干预措施的可能性。 这代表了领养评估的最早应用。 方法直接连接到CTN节点的活动，并确定 促进或延缓采用CTN干预措施。精细化地图的使用 CTN背景下的战略为地图的扩展奠定了基础 CTN节点，以及未来的随机设计，其中特定的干预 采用技术可以通过经验进行测试。

DESCRIPTION: (provided by applicant) National leadership in field of drug abuse treatment has recognized the need to establish effective treatments, and to extend those treatments to more persons seeking treatment. This is reflected in establishment of the NIDA Clinical Trial Networks (CTNs) to study effectiveness through large-scale clinical trials, and in the establishment of CSAT Practice Research Collaboratives (PRCs) to bridge between research and practice. The full promise of these efforts, however, cannot be realized unless interventions with demonstrated effectiveness are adopted into clinical practice. Although available literature comments on factors influencing organizational change, factors influencing adoption of treatment innovation, and the gap between research and practice, there are no systematic efforts to integrate this literature, develop measurement strategies and, using these measures, study intervention adoption in multi-site clinical trials. This is a proposal to develop and apply a Multi-level Assessment Protocol (MAP) to investigate the extent to which behaviorally oriented drug abuse treatment interventions are adopted by community based providers participating in multi-site clinical trials. The proposed project will establish procedures for investigating how well research-based treatment interventions are adopted in the treatment field, identify barriers to intervention adoption, and identify factors that increase or decrease likelihood of adoption. We will develop and field test a MAP strategy in the context of the Matrix methamphetamine multi-site clinical trial, which is not a part of the NIDA CTN. We will then apply the MAP to the CTN Motivational Enhancement Therapy/Motivational Interviewing clinical trial currently in nascent stages. The long-term project goal is to establish strategies, for use in the national CTN, which will increase the likelihood of adoption of clinical trial interventions. This represents the earliest possible application of adoption assessment methods directly to the activities of CTN nodes, and identifies factors that facilitate or retard adoption of CTN interventions. Use of a refined MAP strategy within the CTN context sets the stage for expansion of the MAP across CTN nodes, and for future randomized designs in which specific intervention adoption technologies can be empirically tested.