BIOLOGY AND PATHOBIOLOGY OF GI EPITHELIAL CELLS

总体描述（改编自应用程序） 此申请是为消化系统疾病的竞争性更新 研究核心中心（DDRCC）在芝加哥大学。这个中心？之主要 主题是研究上皮细胞的生物学和病理学， 胃肠道这一解除武装、复员和重返社会协调委员会将继续是一个多学科和 合作奋进涉及70名研究者（31名正式成员和39名 准会员）的临床和基础科学部门， 芝加哥大学生物科学系。其目的是 DDRCC没有改变，并且是：1）与消化系统疾病有关 支持性，综合性，协作性和多学科的研究 方式; 2）增强基础研究能力，建立消化 疾病调查员; 3）鼓励调查员不参与消化道 与疾病相关的研究，成为有兴趣追求的问题， 这一重要的调查领域; 4）制定和实施方案， 培养和建立消化系统疾病相关的年轻研究人员 5）促进新的研究成果转移到 临床领域;以及6）告知其他专业和非专业设置， 消化系统疾病相关领域的成就、机遇和进展 research.芝加哥大学的DDRCC有三个核心实验室 (Cell生物学、分子医学和生物化学与生物物理学）， 消化系统疾病相关的研究，试点和可行性研究和新的 研究者奖计划，以促进年轻和建立参与 研究人员在研究有关消化系统疾病和行政 核心监督整个中心的运作。综上所述各项 目标和组成部分定义了芝加哥大学的DDRCC。

OVERALL DESCRIPTION (Adapted from the application) This application is for the competitive renewal of the Digestive Disease Research Core Center (DDRCC) at the University of Chicago. This Center?s major theme is the study of the biology and pathobiology of epithelial cells of the gastrointestinal tract. This DDRCC will continue to be a multidisciplinary and cooperative endeavor involving 70 investigators (31 full members and 39 associate members) in the clinical and basic science departments of the Division of Biological Sciences at the University of Chicago. The aims of this DDRCC have not changed and are: 1) to foster digestive diseases-related research in a supportive, integrative, collaborative and multidisciplinary manner; 2) to enhance the basic research capabilities of established digestive diseases investigators; 3) to encourage investigators not involved in digestive diseases-related research to become interested in pursuing problems related to this important area of investigation; 4) to develop and implement programs for training and establishment of young investigators in digestive diseases-related research; 5) to facilitate the transfer of new research findings to the clinical area; and 6) to inform others in both professional and lay settings of the accomplishments, opportunities and advances in digestive disease-related research. The DDRCC at the University of Chicago has three core laboratories (Cell Biology, Molecular Medicine, and Biochemistry & Biophysics) to foster digestive diseases-related research, Pilot and Feasibility Studies and New Investigator Award programs to foster participation of younger and established investigators in research related to digestive diseases and an Administrative Core to oversee the operation of the Center as a whole. Taken together, these objectives and components define the University of Chicago's DDRCC.