MECHANICALLY-BASED IMPAIRMENT MEASURES OF LOW BACK PAIN

描述（改编自申请人的描述）：本指导的目标 研究科学家发展奖是让申请人开发 在运动调查中独立所需的研究技能 使用临床和 工具化的措施。拟议研究的长期目标是 了解运动障碍的性质和特异性， 脊柱疼痛的条件，并使用这些信息来设计和测试 这些疾病的康复和预防战略。研究 被设计来测试机械性腰痛的一般假设， （MLBP）的结果，部分原因是腰椎倾向于运动 当移动躯干或四肢时，向特定方向移动。移动的趋势 作为重复的结果， 在日常工作和休闲活动中进行的运动。的 实验将解决（1）MLBP的可区分组是否可以 基于在一个或多个时间段期间测量的方向特定的损伤来识别。 临床检查，（2）之间存在特定的关系 重复进行躯干运动的方向， MLBP患者的运动障碍类型，以及（3） 是MLBP患者躯干肌肉募集模式的改变， 在特定的方向上重复地进行躯干运动。解决这些 假设，来自临床检查的测试数据， 方向性、机械性损伤，以及运动学和 将检查肌电图（EMG）数据。在第一个实验中，数据 MLBP患者的一组方向特异性临床检查变量 将使用以下方法检测是否存在可区分的MLBP组 先进的多元技术第二个实验将比较 和MLBP人群中方向特异性损伤的程度 在特定方向上执行重复的躯干运动，以及控制 组第三个实验将研究臀部和躯干之间的关系 进行重复躯干运动的MLBP和未进行MLBP的人的旋转障碍 旋转运动。最后，躯干肌肉招募模式， 将在MLBP患者队列中比较肢体运动 在特定方向上执行重复的躯干运动，以及控制 组所提出的实验旨在确定 MLBP中的运动损伤，并将这些损伤与特定的， 人们重复进行的日常活动。

DESCRIPTION (Adapted from Applicant's Description): The goal of this Mentored Research Scientist Development Award is to allow the applicant to develop the research skills necessary to be independent in the investigation of movement impairments in people with spinal pain conditions using clinical and instrumented measures. The long term goals of the proposed research are to understand the nature and specificity of the movement impairments found in spinal pain conditions and to use this information to design and test rehabilitation and prevention strategies for these conditions. Studies have been designed to test the general hypothesis that mechanical low back pain (MLBP) results, in part, from a tendency of the lumbar spine to favor movement in a specific direction when moving the trunk or limbs. The tendency to move in a specific direction is proposed to develop as a consequence of repetition of movements performed during daily work and leisure activities. The experiments will address whether or not (1) distinguishable groups of MLBP can be identified based on direction-specific impairments measured during a clinical examination, (2) there is a relationship between the specific directions in which trunk movements are performed repeatedly and specific types of movement impairments identified in people with MLBP, and (3) there are altered patterns of trunk muscle recruitment in people with MLBP that perform trunk movements repeatedly in a specific direction. To address these hypotheses, data from tests from a clinical examination that assesses direction-specific, mechanically-based impairments, as well as kinematic and electromyographic (EMG) data will be examined. In the first experiment, a data set of direction-specific clinical examination variables from people with MLBP will be tested for the presence of distinguishable groups of MLBP using advanced, multivariate techniques. A second experiment will compare the number and extent of direction-specific impairments in a cohort of people with MLBP performing repeated trunk movements in a specific direction, and a control group. A third experiment will examine the relationship between hip and trunk rotation impairments in people with and without MLBP performing repeated trunk rotation movements. Finally, trunk muscle recruitment patterns during extremity movements will be compared in a cohort of people with MLBP performing repeated trunk movements in a specific direction, and a control group. The proposed experiments are designed to determine the nature of the movement impairments in MLBP and to relate these impairments to specific, everyday activities the persons perform repeatedly.