BARRIER ACCEPTABILITY IN CULTURALLY DIVERSE HIV+ WOMEN

描述（根据申请人的描述改编）：委托人 拟议研究的目的是：1）评估女性的可接受性- 控制性障碍方法在种族多样性的人口中， 发达国家和发展中国家，2）发展和测试文化的功效 使用认知/行为策略和经验的敏感干预 培训技巧，促进谈判技巧和应对策略， 增加和维持性障碍使用，3）确定 影响杀微生物剂使用的开始和维持， 艾滋病毒/性传播疾病在目标人群中的传播。 感染艾滋病毒/艾滋病的低收入有色人种妇女是最受忽视的群体之一 和未充分研究的受艾滋病流行影响的人群。选择的网站 因为拟议的研究经费反映了艾滋病毒发病率的两个主要中心 发达国家和发展中国家的妇女：在美国，迈阿密， 佛罗里达和非洲赞比亚的卢萨卡。佛罗里达在美国排名第三 新报告的艾滋病病例;迈阿密-戴德县有最高的 佛罗里达艾滋病发病率。在感染艾滋病毒的少数民族妇女中， 佛罗里达，59%是非洲裔美国人，25%是西班牙裔，16%是海地人。 卢萨卡200万居民中约有25%的人艾滋病毒血清反应呈阳性， 预计到2005年，这一数字将翻一番。 为了实现上述目标，拟议的两个中心临床试验将 随机选择900名不同种族（非裔美国人，西班牙裔， 海地人、高加索人、赞比亚人）感染艾滋病毒/艾滋病的妇女（迈阿密：n = 450; 卢萨卡：n = 450）分为1）认知/行为安全性行为技能组 训练实验条件，2）个人“加强平时照顾” 比较条件或3）“常规护理”对照条件。两个实验 组和比较个人条件将收到一个手动的三个 专门讨论安全性行为和女性控制屏障方法的会议方案 基于纽约安全性行为等级。除了 基线评估和会话评估，长期随访评估 将在6个月和12个月时进行。

DESCRIPTION (Adapted from the applicant's description): The principal objectives of the proposed study are to 1) assess the acceptability of female- controlled sexual barrier methods in ethnically diverse populations in the developed and developing world, 2) develop and test the efficacy of culturally sensitive interventions using cognitive/behavioral strategies and experiential training techniques to facilitate negotiation skills and coping strategies to increase and maintain sexual barrier use and 3) identify factors that influence the initiation and maintenance of microbicide use to reduce the transmission of HIV/STDs in the target populations. Low income women of color living with HIV/AIDS are among the most neglected and understudied populations affected by the AIDS epidemic. The sites selected for the proposed research grant reflects two major epicenters of HIV incidence in women in the developed and developing worlds: in the United States, Miami, Florida, and in Africa, Lusaka, Zambia. Florida ranks third in the United States for newly reported AIDS cases; Miami-Dade County has the highest incidence of HIV/AIDS in Florida. Among minority women living with HIV in Florida, 59% are African American, 25% are Hispanic, and 16% are Haitian. Approximately 25% of Lusaka's 2 million inhabitants are HIV seropositive; this figure is projected to double by 2005. To accomplish the above objectives, the proposed two-site clinical trial will randomize a total of 900 ethnically diverse (African American, Hispanic, Haitian, Caucasian, Zambian) women living with HIV/AIDS (Miami: n = 450; Lusaka: n = 450) into 1) a group cognitive/behavioral safer sex skills training experimental condition, 2) an individual "enhanced usual care" comparison condition or 3) a "usual care" control condition. Both experimental group and comparison individual conditions will receive a manualized three session program devoted to safer sex and female controlled barrier methods based upon the New York Hierarchy of safer sexual practices. In addition to baseline assessment and session evaluations, long term follow-up assessments will be carried out at 6 and 12 months.