BARRIER ACCEPTABILITY IN CULTURALLY DIVERSE HIV+ WOMEN

描述(改编自申请人的描述)：委托人 这项拟议研究的目标是：1)评估女性-- 美国不同种族人群中的受控性障碍方法 发达和发展中世界，2)发展和检验文化的功效 使用认知/行为策略和经验的敏感干预 培训技巧以促进谈判技能和应对策略，以 增加和维持性障碍的使用，以及3)确定 影响杀菌剂使用的启动和维持，以减少 艾滋病毒/性传播疾病在目标人群中的传播。 感染艾滋病毒/艾滋病的低收入有色人种妇女是最被忽视的群体之一 以及对受艾滋病疫情影响的人群研究不足。选定的站点 因为建议的研究拨款反映了艾滋病毒发病率的两个主要中心 发达国家和发展中国家的女性：在美国、迈阿密、 佛罗里达，在非洲，卢萨卡，赞比亚。佛罗里达州在美国排名第三 新增艾滋病病例的州；迈阿密-戴德县是最高的 佛罗里达州的艾滋病毒/艾滋病发病率。年在感染艾滋病毒的少数族裔妇女中 佛罗里达州，59%是非洲裔美国人，25%是西班牙裔，16%是海地人。 卢萨卡200万居民中约25%的人艾滋病毒血清呈阳性； 预计到2005年，这一数字将翻一番。 为了实现上述目标，拟议的两个地点的临床试验将 将总共900名不同种族的人(非洲裔美国人，西班牙裔， 海地人、高加索人、赞比亚人)感染艾滋病毒/艾滋病的妇女(迈阿密：450人； 卢萨卡：450)融入1)一组认知/行为安全的性行为技能 训练实验条件，2)个人“强化日常护理” 比较条件或3)“常规护理”控制条件。都是实验性的 组别和比对个别情况将收到三份手册 致力于安全性行为和女性控制障碍方法的会议计划 基于纽约安全性行为的等级制度。除了……之外 基线评估和届会评估、长期后续评估 将在6个月和12个月时进行。

DESCRIPTION (Adapted from the applicant's description): The principal objectives of the proposed study are to 1) assess the acceptability of female- controlled sexual barrier methods in ethnically diverse populations in the developed and developing world, 2) develop and test the efficacy of culturally sensitive interventions using cognitive/behavioral strategies and experiential training techniques to facilitate negotiation skills and coping strategies to increase and maintain sexual barrier use and 3) identify factors that influence the initiation and maintenance of microbicide use to reduce the transmission of HIV/STDs in the target populations. Low income women of color living with HIV/AIDS are among the most neglected and understudied populations affected by the AIDS epidemic. The sites selected for the proposed research grant reflects two major epicenters of HIV incidence in women in the developed and developing worlds: in the United States, Miami, Florida, and in Africa, Lusaka, Zambia. Florida ranks third in the United States for newly reported AIDS cases; Miami-Dade County has the highest incidence of HIV/AIDS in Florida. Among minority women living with HIV in Florida, 59% are African American, 25% are Hispanic, and 16% are Haitian. Approximately 25% of Lusaka's 2 million inhabitants are HIV seropositive; this figure is projected to double by 2005. To accomplish the above objectives, the proposed two-site clinical trial will randomize a total of 900 ethnically diverse (African American, Hispanic, Haitian, Caucasian, Zambian) women living with HIV/AIDS (Miami: n = 450; Lusaka: n = 450) into 1) a group cognitive/behavioral safer sex skills training experimental condition, 2) an individual "enhanced usual care" comparison condition or 3) a "usual care" control condition. Both experimental group and comparison individual conditions will receive a manualized three session program devoted to safer sex and female controlled barrier methods based upon the New York Hierarchy of safer sexual practices. In addition to baseline assessment and session evaluations, long term follow-up assessments will be carried out at 6 and 12 months.