Locomotor Adaptation Following Podokinetic Stimulation

描述：(申请人提供) 这项研究的主要目的是更好地了解 对改变的感觉输入做出的运动适应。建议数 研究集中在感觉信息从“双脚向上”传递的作用。 运动轨迹的自适应。最近的工作表明，以下是 足动刺激(即，在旋转跑步机上原地踏步 20-40分钟)，蒙着眼睛的受试者被要求原地踏步或走在 静止表面上的直线会在不知不觉中相对于 太空。这种适应被称为足动后旋转(PKAR)，有两个 不同的组件： 1)时间常数为5-10分钟的短期效应；2)长期效应 影响的时间常数为1-2小时。对PKAR有更全面的了解 可能有助于为有平衡感的人制定康复策略 还有步态障碍。计划中的实验将使用足动刺激。 作为评估感觉输入改变对控制的影响的一种手段 在运动过程中的定向。《特殊目标I》考查运动学和 PKAR的肌电特点。特定目标2解决了 前向行走对其他行为和要求的适应性研究 左右肢是否能独立适应。具体目标3 探讨小脑在习得和维持脑功能中的作用。 运动对足部运动刺激的适应性

DESCRIPTION:(provided by applicant) The major objective of this research is to gain a better understanding of locomotor adaptations made in response to altered sensory inputs. The proposed studies focus on the role of sensory information relayed from the "feet up" in the adaptation of locomotor trajectory. Recent work has shown that, following podokinetic stimulation (i.e., stepping in-place on a rotating treadmill for 20-40 minutes), blindfolded subjects asked to step in-place or walk in a straight line on a stationary surface will unknowingly rotate relative to space. This adaptation, called podokinetic after-rotation (PKAR), has two distinct components: 1) a short-term effect with a time constant of 5-10 minutes and 2) a long-term effect with a time constant of 1-2 hours. A more complete understanding of PKAR may be useful for developing rehabilitation strategies for people with balance and gait disorders. The proposed experiments will use podokinetic stimulation as a means of assessing the effects of altered sensory inputs on the control of orientation during locomotion. Specific Aim I examines the kinematic and electromyographic features of PKAR. Specific Aim 2 addresses the generalizability of adaptations of forward walking to other behaviors and asks whether the left and right limbs can be independently adaptated. Specific Aim 3 explores the role of the cerebellum in the acquisition and maintenance of locomotor adaptations to podokinetic stimulation