HIGH RESOLUTION THREE DIMENSIONAL ULTRASOUND IMAGING

描述(改编自申请者摘要)：该建议将继续 高分辨率实时体积成像系统(RTVI)的研制 系统。当前RTVI的最新临床经验支持其强大的 无创评估心肌和心功能的可能性。 可以在逐个心跳的基础上获得心室体积和质量，而无需 几何假设。RTVI提高了早期应力回波的准确性 检测灌注缺陷，减少患者检查时间，以及 消除了用于扫描的儿科镇静剂。改善了图像质量和 视域对于充分利用RTVI的好处是至关重要的。 在实施：1方面取得重大进展 并行处理扫描仪，最多可独立发送和接收512个 这将导致改善图像质量的频道。数据采集率 通过从同一孔径发射多个超声波束来增加 接二连三地。这项研究可能对克服 降低了RTVI中的回波灵敏度。项目在假设的基础上继续 使用2D阵列、多波束发射和并行接收 可以有效地实现处理，以提高分辨率，领域 实时体积图像的查看、动态范围和灵敏度。这 续订申请计划完成小说的构建和测试 高分辨率实时扫描仪及其与当前的性能比较 扫描仪(2D和3D)。它建议优化和实现杜克独特的 用于二维阵的多波束传输系统。这项提议还旨在 开发一种独特的、非常高速的、能够在线扫描的转换系统 用于改进可视化和解剖学的体数据的渲染 身份证明。为了进一步提高分辨率和图像质量，本提案 将开发新型专用变送器附近的IC以允许使用 超过1000个有源元件，而不会进一步增加电缆尺寸。一旦这一次 障碍被消除，团队将实施必要的硬件来 将接收器数量增加到1000个以上。

DESCRIPTION (Adapted from Applicant's Abstract): This proposal will continue the development of a high resolution real time volumetric imaging (RTVI) system. Recent clinical experience with current RTVI supports its strong potential for noninvasive evaluation of the myocardium and cardiac function. Ventricular volumes and mass can be obtained on a beat-to-beat basis without geometric assumptions. RTVI improves accuracy of stress echo for early detection of perfusion deficits, reduces patient examination time, and eliminates pediatric sedation for scanning. Improvements in image quality and field of view are essential in fully exploiting the benefits of RTVI. Significant progress has been made towards the implementation of a 64:1 parallel processed scanner featuring up to 512 individual transmit and receive channels which will lead to improved image quality. Data acquisition rates have been increased by transmitting multiple ultrasound beams from the same aperture in rapid succession. This research could have major importance in overcoming reduced echo sensitivities in RTVI. The project continues on the hypothesis that using 2D arrays, multiple beam transmissions, and receive parallel processing can be effectively implemented to improve the resolution, field of view, dynamic range, and sensitivity of real time volumetric images. This renewal application proposes to complete construction and testing of the novel high resolution real time scanner and compare its performance with current scanners (2D and 3D). It proposes to optimize and implement Duke's unique multi-beam transmission system for 2D arrays. This proposal also aims to develop a unique, very high speed, scan conversion system capable of on line rendering of volumetric data for improved visualization and anatomical identification. To further improve resolution and image quality, this proposal will develop novel specialized IC's near the transducer to permit the use of over 1000 active elements without further increase in cable size. Once this barrier is eliminated, the team will implement the necessary hardware to increase receiver count to over 1000 channels.