Toward the Neural Basis of Episodic Memory

描述（由申请人提供）：情景记忆是指能够 记住我们经历中的具体事件。这种能力是脆弱的， 受到各种大脑损伤的影响，包括早期阶段的 老年痴呆症？s病，正常衰老，缺血性事件， 治疗癫痫、闭合性脑损伤和精神分裂症。本申请 把申请人聚在一起？在情景认知建模方面的经验 与赞助商的合作？的神经生理学经验，建立一个 大脑区域的详细模型最密切地参与了情节 记忆计算技术将用于开发 以与已知生理学一致的方式建立模型。的能力 描述人类记忆的表现也将被评估。

DESCRIPTION (provided by applicant): Episodic memory refers to the ability to remember specific occurrences from our experience. This ability is fragile, being affected by diverse brain insults, including the early stages of Alzheimer?s disease, normal aging, ischemic incidents, resection for the treatment of epilepsy, closed head injury, and schizophrenia. This application brings together the applicant?s experience in cognitive modeling of episodic association with the sponsor?s experience in neurophysiology to build a detailed model of the region of the brain most closely involved in episodic memory. Computational techniques will be used to develop the components of the model in a way that is consistent with known physiology. Its ability to describe human memory performances will also be evaluated.