LOS ANGELES HIV PREVENTION TRIALS UNIT

该申请将在洛杉矶县建立一个HIV预防试验联盟（HPTC），该联盟将是NIH HIV预防试验网络（HPTN）下的一个单位，并将与NIH HIV预防试验网络（HPTN）密切合作。洛杉矶HPTC将为HPTN带来以下四个团体之间强有力的本地合作伙伴关系：1)能够在历史上服务不足的社区为预防研究提供支持的社区倡导者和教育工作者；2)具有高危人群工作经验的社区研究人员和流行病学家；3)能够设计和快速实施第一、二、三期行为和治疗性预防以及杀微生物剂试验的行为科学家和临床医生；4)基础病毒学家和免疫学家致力于识别和测量HIV保护性免疫的关键相关因素。洛杉矶HPTC是由社区利益相关者和倡导者、来自四个学术机构（南加州大学、加州大学洛杉矶分校、加州州立大学长滩分校和查尔斯·r·德鲁医学与科学大学）的研究人员、为非洲裔美国人和拉丁裔服务的社区护理和预防团体以及洛杉矶的同性恋和双性恋社区（To Help Everyone (T.H.E.)）组成的。以及艾滋病流行病学和预防研究方面的专家。该联盟的目标是为促进对有效的行为、杀微生物和治疗干预措施的理解做出重大贡献，这些干预措施将减少艾滋病毒的传播，同时为预防研究建立社区支持。

This application will establish in Los Angeles County a HIV Prevention Trials Consortium (HPTC) that will be a unit under and will work in close collaboration with the NIH HIV Prevention Trials Network (HPTN). The Los Angeles HPTC will bring to the HPTN a strong local partnership between the following four groups: 1) community advocates and educators who can build support for prevention research in historically underserved communities 2) community-based researchers and epidemiologists with experience working with high-risk populations 3) behavioral scientists and clinicians capable of designing and rapidly implementing Phase I, II and III behavioral and therapeutic prevention and microbicide trials, and, 4) basic virologists and immunologists committed to identifying and measuring the key correlates of protective immunity against HIV. The Los Angeles HPTC has been formed by bringing together community stakeholders and advocates, researchers from four academic institutions (University of Southern California, University of California at Los Angeles, California State University, Long Beach and the Charles R. Drew University of Medicine and Sciences), community-based care and prevention groups serving the African American and Latino, and gay and bisexual communities of Los Angeles (To Help Everyone (T.H.E.) Clinic, AltaMed, and the Gay and Lesbian Center) and experts in HIV epidemiology and prevention research. The goal of this consortium is to make significant contributions to advancing the understanding of effective behavioral, microbicidal and therapeutic interventions that will reduce HIV transmission while building community support for prevention research.