PSYCHOBIOLOGICAL PATHWAYS--OSTEOARTHRITIS INTERVENTION

描述(改编自S摘要)：骨性关节炎是一种 一种以疼痛和功能性疾病为特征的慢性不治之症 有局限性，在65岁及以上的成年人中最为普遍。这个 拟议研究的主要目的是确定骨性关节炎患者和他们的 配偶照顾者从教育中获得更大的健康益处 针对这两个人的干预，而不是只针对 病人。患有骨性关节炎的老年人及其配偶将被随机分配 三种情况中的一种：常规护理、患者教育或合并患者 夫妻教育。要衡量的结果将包括面对面的面试， 基于表现的身体机能测量，观察性测量 配偶互动，以及心血管和内分泌测量。

DESCRIPTION (adapted from investigator?s abstract): Osteoarthritis (OA) is a chronic, incurable disease that is often characterized by pain and functional limitations and is most prevalent in adults ages 65 years of age and older. The primary aim of the proposed study is to determine if OA patients and their spousal caregivers experience greater health benefits from an educational intervention targeted at both individuals than from education directed only at the patient. Older adults with OA and their spouses will be randomly assigned to one of three conditions: usual care, patient education, or combined patient couples education. Outcomes to be measured will include in-person interviews, performance-based measures of physical functioning, observational measures of spouse interactions, and cardiovascular and endocrine measures.