IMPROVEMENT OF ANIMAL RESOURCES

描述(由申请人提供)： 这是一份申请翻新位于南加州大学健康科学校区的伊莱恩·史蒂夫利·霍夫曼医学研究中心(HMRC)的动物收容所的申请。本申请中详述的翻修计划的具体目标包括：1)显著提高为狗和猪等大型动物物种提供充分动物护理的能力，并大幅增加这些物种的收容能力。房间卫生、动物的社会和行为条件以及员工的健康和安全都将显著改善。2)在该设施的笼子洗涤区提供散装消毒器，以改善屏障条件下的住房，以扩大老鼠的数量。3)为通风系统、货运电梯提供应急备用发电机，并为设施提供应急照明。4)改善设施的动物尸检和手术区域。5)将翻新后的设施作为改善和集中在大学的动物设施的整体计划的一部分。有具体的架构计划和系统的方法来实施设施翻新，这将有助于南加州大学生物医学研究的未来增长。翻新后的设施将完全满足《保护和使用实验动物指南》、美国农业部(USDA)法规和所有其他相关法规的要求。南加州大学行政部门承诺为这项申请提供配套资金，这表明了南加州大学对动物护理和利用项目的总体支持。

DESCRIPTION (provided by applicant): This is an application to renovate the animal housing facilities in the Elaine Stevely Hoffman Medical Research Center (HMRC) on the Health Sciences Campus of the USC. The specific aims of the renovation plan as detailed in this application include the following: 1) To significantly improve the ability to provide adequate animal care to large animal species such as dogs and swine, and to greatly increase the capacity for housing these species. Room sanitation, social and behavioral conditions for the animals, and employee health and safety would all improve dramatically. 2) To provide a bulk sterilizer in the cage wash area of this facility to provide for improved housing under barrier conditions for expanding populations of mice. 3) To provide an emergency standby power generator to the ventilation system, freight elevator, and emergency lighting for the facility. 4) To improve the animal necropsy and surgery areas of the facility. 5) To use the renovated facility as part of an overall plan for improved and centralized animal facilities at the University. There are specific architectural plans and a systematic approach to implementation of a facility renovation that will help for future growth in biomedical research at the USC. The renovated facility will fully meet the requirements of the Guide for the Care and Use of Laboratory Animals, United States Department of Agriculture (USDA) regulations, and all other relevant regulations. There is a commitment from the USC administration for matching funds to this application, demonstrating the overall support of the University for the animal care and use program.