IMPROVING INSTITUTIONAL ANIMAL RESOURCES

描述（由申请人提供）： IUSM在联邦政府资助的使用基因工程小鼠（GEM）的研究中取得了显著增长。 这种增长使癌症、基因修复和基因治疗的研究几乎呈指数级增长。为了维持这种增长并满足相关研究人员的需求，特别是微生物学和免疫学系以及儿科血液学系的研究人员，需要增加这些动物的住房和辅助空间。 本申请将通过提供额外的5，600平方英尺的空间来解决这个问题。英尺用于这些小鼠的圈养、手术室和储存空间，该区域由放射科腾出，与主要动物设施相邻。 此外，本项目将在笼清洗设施中提供第二台高压灭菌器，使其能够处理本研究产生的笼和其他材料的增加负载。

DESCRIPTION (provided by applicant): The IUSM has enjoyed a dramatic increase in federally funded research using genetically engineered mice (GEMs). This growth has paralleled nearly exponential rise in research on cancer, gene repair, and gene therapy. To sustain this growth and meet the needs of the involved researchers, especially those in the Department of Microbiology and Immunology and in the Division of Pediatric Hematology, there is need to increase the housing and ancillary space available for these animals. The present application will address this issue by providing an additional 5,600 sq. ft. for housing, procedure rooms, and storage space for these mice in an area vacated by the Radiology Department that is adjacent to the main animal facility. Additionally, this project will provide a second autoclave in the cage wash facility that will enable it to process the increased load of cages and other materials generated by this research.