Web-based Client-Server Alcohol & Drug Abuse Assessment

这一第二阶段项目的总体目标是扩展和改进基于网络的客户端-服务器软件系统(“JavaSCAN[TM]”)，该软件系统已成功创建，并在第一阶段被证明是可行的。按计划，该系统使用Java客户端和网络数据库服务器实施，并使用世界卫生组织(WHO)神经精神病学临床评估时间表(SCAN 2.1版)中的第11节(“酒精的使用”)和第12节(“酒精以外的精神活性物质的使用”)作为对酒精和其他药物的使用、滥用和依赖的半结构化标准化临床评估的基础。第二阶段的工作针对已确定的市场需求。在第一阶段经验的基础上，计划增加功能，为药物滥用和依赖研究市场创造一种有用的产品，包括临床试验。这个软件系统可以服务的两个重要领域是(1)评估(数据收集过程)和(2)研究管理(项目管理)。评估功能涉及：共病研究、增强的时间测量、已建立的心理测量学和诊断分类。研究管理职能涉及：组织研究中心、项目、工作人员和学科；以及多中心分配和管理评估过程和数据管理。为满足这些需求，第二阶段的目标是：(1)增加其他扫描科，以支持共病研究；(2)扩展数据模型和接口，以支持增强的时间测量；(3)心理测量性能研究；(4)整合自动诊断分类功能；以及(5)在多个地点实施项目和数据管理的功能和用户界面。现场测试将在圣路易斯的华盛顿大学进行。拟议的系统有可能通过促进有效的评估标准化，导致酒精、药物和精神健康研究和服务方面的进一步创新(第三阶段及以后)，从而帮助创建集中和汇集的临床数据库。这类数据库将反过来为进一步的研究和技术开发提供基础，例如科学管理和优化评估和决策，或将社区活动与大学研究联系起来。拟议的商业应用：与酒精和药物滥用和依赖的系统评估和确定有关的所有领域都存在商业潜力，包括流行病学和服务研究、教育、管理保健和工业。

The overall goal of this Phase II project is to extend and refine the web- based client-server software system ("JavaSCAN [TM]"), which was successfully created and shown feasible in Phase I. As planned, the system was implemented using a Java client and a web database server, and Sections 11 ("Use of Alcohol") and 12 ("Use of Psychoactive Substances other than Alcohol") from the World Health Organization (WHO) Schedules for Clinical Assessment in Neuropsychiatry (SCAN version 2.1) were used as the basis for semi-structured standardized clinical assessment of alcohol and other drug use, abuse, and dependence. Phase II efforts address identified market needs. Based upon Phase I experiences, additional functionality is planned to create a useful product for the substance abuse and dependence research markets, including clinical trials. Two important areas in which this software system can serve are (1) assessment (data collection process) and (2) research administration (project management). Assessment functions address: study of co-morbidity, enhanced temporal measurement, established psychometrics, and diagnostic classification. Research administration functions address: organizing research centers, projects, staff, and subjects; and multi-center distribution and management of the assessment process and data management. To meet these needs, Phase II Aims are: (1) addition of other SCAN sections to support studies of co-morbidity; (2) extension of the data model and interface to support enhanced temporal measurement; (3) study of psychometric performance; (4) integration of automated diagnostic classification functions; and (5) implementation of functions and user interfaces for project and data management across multiple sites. Field testing will be carried out at Washington University in St. Louis. The proposed system has potential to lead to further (Phase III and beyond) innovations in alcohol, drug, and mental health research and services by fostering efficient standardization of assessment, thus helping create centralized and pooled clinical databases. Such databases would in turn provide a basis for further research and technical developments, such as scientific management and optimization of assessment and decision-making, or in linking community activities and university research. PROPOSED COMMERCIAL APPLICATIONS: Commercial potential is present in all areas related to systematic assessment and ascertainment of alcohol and drug abuse and dependence, including epidemiology and services research, education, managed care, and industry.