Behavioral Genetic Study of Religiosity and Alcoholism

描述(由申请人提供)：虽然宗教和灵性有 一直被认为影响着广泛的人类经历， 对这一现象的科学研究还没有跟上增长的步伐 它与健康、医疗和酗酒问题相关的证据。这 申请寻求小额赠款支持(R03)用于二次分析，涉及 来自NIAAA支持的三个涉及青少年的大型孪生项目的数据 双胞胎和成年双胞胎。根据这些数据，我们可以详细说明最近的行为- 对宗教和宗教之间的关系有影响的基因发现 酗酒；特别是宗教如何影响传播和 几代人之间酗酒的发展。具体目标是：(1) 考察宗教和那些被认为是 是酗酒的遗传先驱以及宗教和酗酒之间的关系 变量本身；(2)考察宗教在 家族酗酒史对子女酒精中毒影响的定量化研究 和其他阴性结果；(三)进行初步检查 与未来的研究方向相关，包括(A)多维 宗教信仰的性质；(B)宗教信仰与其他 个体差异变量；(C)宗教信仰与其他模型的关系 酒精中毒病因学；和(D)对发育问题的审议(每个 Data Set使用队列顺序设计)关于 对酒精中毒和其他障碍的发展和进程的宗教信仰。

DESCRIPTION (provided by applicant): Although religion and spirituality have always been thought to influence a wide range of human experience, the scientific study of this phenomenon has not kept pace with the growing evidence of its relevance to health, medical, and alcoholism concerns. This application seeks small grant support (R03) for secondary analyses involving data from three large-scale NIAAA-supported twin projects involving adolescent twins and adult twins. Given these data, we can elaborate on recent behavioral- genetic findings that have bearing on the relationship between religion and alcoholism; in particular how religion can impact the transmission and development of alcoholism across generations. The specific aims are: (1) to examine interaction of effects between religion and those variables thought to be genetic precursors to alcoholism and between religion and alcoholism variables per se; (2) to examine the moderating role that religion can play in qualifying the impact of family history of alcoholism on offspring alcoholism and other negative outcomes, and (3) to conduct preliminary examinations relevant to future research directions including (a) the multidimensional nature of religiosity; (b) the relationship between religiosity and other individual difference variables;(c) how religiosity is related to other models of alcoholism etiology; and (d) consideration of developmental issues (each data set utilizes a cohort sequential design) regarding the moderating role of religiosity on development and course of alcoholism and other disorders.