GRAVES HALL VIVARIUM RENOVATION

俄亥俄州立大学致力于在动物研究方面追求卓越的标准。获得并保持实验室动物护理认证和评估协会（AAALAC）的认证是大学衡量实现这一目标的手段之一。大学实验动物资源（ULAR）于1990年7月1日在其目前的配置中成立，以巩固和集中在大学哥伦布校区和三个校外地点的所有生物医学动物研究的动物护理计划。所有人员、设备和设施都从各自的学院转移到联合大学。该中心是美国最大的大学动物护理项目之一，拥有14个独立的动物设施，在哥伦布校区有3个手术中心，在校外有4个手术中心，为121个学院、7所学院和研究生院的教师提供动物研究支持。在2000财政年度，动物资源中心为超过300名有原则的研究人员提供了超过681种动物实验方案。在俄亥俄州立大学，大约74%的动物使用发生在主校区的五个独立的舍内。最大的怀斯曼大厅，最近进行了自1968年建成以来的第一次升级。我们在主校区的第二大动物饲养场，格雷夫斯大厅，建于1970年，也需要升级和翻新，以适应在“最先进的”动物护理方面发生的巨大变化。为了保持对俄亥俄州立大学研究用动物的高标准护理，并为研究人员提供能够容纳目前用于研究的动物的设施，这些动物可能具有免疫功能低下、生物危险、放射性或长期饲养，格雷夫斯动物设施必须翻新。ULAR人员已经确定了设施中的问题区域，如果在不久的将来不加以纠正，可能会影响我们维持AAALAC认证的能力。因此，该设施在ULAR中具有最高的翻新优先级。该提案将为这项改造提供资金，并允许俄亥俄州立大学为研究动物提供高质量的动物住房。

The Ohio State University is committed to pursue a standard of excellence in animal research. Attaining and maintaining accreditation by the Association for the Accreditation and Assessment of Laboratory Animal Care (AAALAC) is one of the means used by the University to measure accomplishment of this objective. The University Laboratory Animal Resources (ULAR) was formed in its present configuration on July 1, 1990 to consolidate and centralize the animal care program for all biomedical animal research on the University's Columbus campus and 3 off-campus locations. All personnel, equipment, and facilities were transferred from their respective colleges to ULAR. ULAR supports one of the nation's largest university animal care programs of 14 separate animal facilities, 3 surgeries on the Columbus campus and 4 off-campus locations, supporting animal research for the faculty of 121 colleges, 7 schools, and the Graduate School. In fiscal year 2000, ULAR provided animal resource services to over 300 principled investigators with over 681 animal protocols. Approximately 74 percent of the animal use at The Ohio State University occurs on the main campus complex in five separate vivaria. The largest vivarium Wiseman Hall, was recently upgraded for the first time since it was built in 1968. Our second largest vivarium on the main campus, Graves Hall, was built in 1970 and is also in need of upgrade and renovation to accommodate the tremendous changes that have occurred in the "state of the ar5t" care available for animals. In order to maintain a high standard of care for the research animals used at The Ohio State University, and provide the investigators with facilities that are capable of housing the animals used in research today that may be immunocompromised, biohazardous, radioactive, or in long-term holding, the Graves animal facility must be renovated. ULAR personnel have identified problem areas in the facility which may compromise our ability to maintain AAALAC accreditation if not corrected in the near future. This facility therefore has the highest renovation priority in ULAR. This proposal will provide for this renovation and allow The Ohio State University to provide quality animal housing for the research animals.