POST PROCESSING & PACKAGING OF ELECTRODES: BIOPOLYMER & CHRONIC IMPLANTS

除了皮质的经典探头应用领域外， 深部结构，周围神经和神经假体，还有 有兴趣使用探头从其他领域进行记录，包括 心肌和组织切片。心肌，如外周的心肌 神经，是硅探针的一种具有挑战性的准备，因为 穿透困难，结构的相对运动是 非常大。卡西奥博士与纳格尔博士合作，一直在 成功记录到兔脑缺血时的纵向兴奋 乳头肌。该小组还提供了关于激活 为了将阻抗降低到适合他们的水平的Ir位置 录音。来自几个学科的调查人员一直在追查 使用探针从组织切片记录的方法，包括 视网膜和火蜥蜴嗅球。

In addition to the classic probe application areas of cortical, deep structures, peripheral nerve and neural prostheses, there is also interest in using the probes to record from other areas including cardiac muscle and tissue slices. Cardiac muscle, as with peripheral nerve, is a challenging preparation for silicon probes in that penetration is difficult and the relative movement of the structure is very large. Dr. Cascio, in collaboration with Dr. Nagle, has been successful in recording longitudinal activation in an ischemic rabbit papillary muscle. This group has also presented data on activation of the iridium sites to reduce impedances to levels suitable for their recordings. Investigators from several disciplines have been pursuing methods to use probes for recording from tissue slices, including retina and salamandar olfactory bulb.