Shared Instrument Grant: Volume CT

该提案要求为MGH CT计划购买卷CT(VCT)系统提供部分支持。该仪器由安装在标准高速螺旋CT机架上的高分辨率全场面板数字探测器组成。建议的VCT系统具有卓越的空间(约150)和时间分辨率(约0.5秒)能力。VCT系统的使用将大大加强NIH资助的一组研究人员的研究努力。该系统可以支持高分辨率(易损斑块的特征、心肌结构、淋巴结成像和代谢骨研究)和功能(心功能、组织灌注)成像研究。该应用程序包含11个主要项目，包括代表不同学科(心脏病学、肿瘤学、神经学、放射学和外科)、波士顿地区机构(MGH、儿童医院和哈佛灵长类中心)和NIH资金来源(NCI、NHLBI、VIA、NIAMS、NINDS)的广泛用户基础。必要的行政和技术指导已经到位，以确保这种仪器的有效利用VCT系统，具有现有CT系统所不具备的能力，将是一项主要资产，将是NIH资助的研究人员社区的主要资产，并可能导致成像研究的重大创新。

This proposal requests partial support for the purchase of a volume CT (VCT) system for the MGH CT program. The proposed instrumentation consists of a high-resolution full-field panel digital detector mounted to a standard high-speed helical CT gantry. The proposed VCT system possesses exceptional spatial (approximately 150) and temporal resolution (approximately 0.5 sec) capabilities. The availability of the VCT system will significantly enhance the research efforts of a group of NIH funded investigators. The system can support both high resolution (characterization of vulnerable plaque, myocardial structure, lymph node imaging and metabolic bone studies) and functional (cardiac function, tissue perfusion) imaging research. The application contains eleven major projects are comprised of a broad base of users representing various disciplines (cardiology, oncology, neurology, radiology and surgery), Boston area institutions (MGH, Childrens Hospital and the Harvard Primate Center) and NIH funding sources (NCI, NHLBI, VIA, NIAMS, NINDS). The necessary administrative and technical direction is already in place to ensure efficient utilization of this instrumentation The VCT system, with capabilities not available on existing CT systems, will be a major asset, will be a major asset to a community of NIH funded investigators and likely lead to major innovations in imaging research.