Cardiac MR and CT Research

心脏 MR 和 CT 研究

• 批准号: 7924151
• 负责人: THOMAS J BRADY
• 金额: $ 33.81万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7924151
• 关键词: Cardiac; Research

DESCRIPTION (provided by applicant): We seek continued NIH support for our Training Program in cardiac imaging research. Funds are requested to support 8 fellows annually. Our program emphasizes the education of basic (PhD) and clinical (MD) scientists in modern cardiac magnetic resonance (MR), positron emission tomography (PET) and computed tomography (CT) imaging science. Our goal is to develop future leaders of cardiac imaging, emphasizing novel developmental and translational research. The training program, based in the MGH Cardiac MR-PET-CT Program, is a joint cardiology and radiology program, a model which greatly enhances opportunities for collaboration. The curriculum consists of didactic lectures including the clinical effectiveness course at the Harvard School of Public Health, laboratory exercises and individual research projects. A major strength of the Program is our outstanding faculty, each of whom are pursuing research at the cutting-edge of cardiac imaging science. The faculty consists of 21 MD and/or PhD scientists with expertise in cardiology, radiology, physics, computer science and outcomes research. Collectively they have over 50 active extramural grants and have supervised over 250 pre/post doctoral fellows in various aspects of basic and clinical cardiac imaging research. Extensive collaboration among the faculty, trainees, and accomplished investigators throughout the MGH, Harvard Medical School and MIT communities, further increase the Program's scientific impact. Broad exposure to highly motivated scientists and committed mentors, with an emphasis on individual scientific excellence, provide the conditions for the successful training of leaders in the use of these important technologies in cardiology. During the initial four years of NIH support, all NIH trainee positions were filled, and trainees authored or coauthored over 50 peer-reviewed publications. All finished trainees obtained staff positions in academic medical centers or continued in academic training programs. To enhance the program we have added technical faculty and novel equipment offering additional research opportunities for trainees in evolving areas of cardiac imaging science including FDG PET imaging of plaque activity, molecular imaging using optical and MR probes, 9.4T imaging of animal models, novel cardiac image reconstruction approaches and simultaneous imaging of stenosis and function during chemical stress using a dual source cardiac CT.

描述（由申请人提供）：我们寻求 NIH 对我们的心脏成像研究培训计划的持续支持。每年请求资金支持 8 名研究员。我们的项目强调现代心脏磁共振（MR）、正电子发射断层扫描（PET）和计算机断层扫描（CT）成像科学方面的基础（博士）和临床（医学博士）科学家的教育。我们的目标是培养心脏成像领域的未来领导者，强调新颖的发展和转化研究。该培训项目以 MGH 心脏 MR-PET-CT 项目为基础，是心脏病学和放射学联合项目，这种模式极大地增加了合作机会。该课程包括教学讲座，包括哈佛大学公共卫生学院的临床有效性课程、实验室练习和个人研究项目。该项目的主要优势是我们优秀的教师队伍，他们每个人都在进行心脏成像科学的前沿研究。该学院由 21 名医学博士和/或博士科学家组成，他们在心脏病学、放射学、物理学、计算机科学和成果研究方面拥有专业知识。他们总共拥有 50 多项活跃的校外资助，并在基础和临床心脏成像研究的各个方面指导了 250 多名博士前/后研究员。麻省总医院、哈佛医学院和麻省理工学院的教员、实习生和有成就的研究人员之间的广泛合作，进一步提高了该项目的科学影响力。广泛接触积极主动的科学家和忠诚的导师，并强调个人的科学卓越性，为成功培训领导者使用这些重要的心脏病学技术提供了条件。在 NIH 支持的最初四年中，所有 NIH 实习生职位均已填补，实习生撰写或合着了 50 多篇同行评审出版物。所有完成培训的学员都获得了学术医疗中心的工作人员职位或继续参加学术培训计划。为了加强该计划，我们增加了技术人员和新颖的设备，为心脏成像科学不断发展的领域的学员提供额外的研究机会，包括斑块活动的 FDG PET 成像、使用光学和 MR 探针的分子成像、动物模型的 9.4T 成像、新颖的心脏图像重建方法以及使用双源心脏 CT 对化学应激期间的狭窄和功能进行同步成像。