COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY

这个应用程序的目的是记录Johns的能力 霍普金斯大学作为一个有效和富有成效的参与者 临床中心在拟议的多中心临床试验中，题为 “协作性青光眼初始治疗研究”(CIGTS)。这项研究是 目的评价开角型青光眼的早期治疗 更有效的方法是采取循序渐进的医疗方案或通过 一种外科手术方法。约翰霍普金斯大学临床中心 将通过确定和招募符合条件的人员参与CIGTS 患者，执行由 CIGTS的协调中心，并在研究手册中定义 手术，跟踪和保留研究患者，记录和 将研究数据传输到协调中心，并做出贡献 提交CIGTS结果的报告。 这份申请描述了约翰霍普金斯大学的能力 临床中心每年招收约29名患者，基于 根据在3个月内对患者资格进行的试点研究 句号。提供了我们的计划的详细信息，以确定、招募、 跟随并留住这些患者，我们始终如一地获得 关于治疗结果的高质量数据，以及 我们中心内可提供的人员和设施来执行 CIGTS《操作手册》的规定。

The intent of this application is to document the ability of the Johns Hopkins University to participate as an effective and productive clinical center in the proposed multicenter clinical trial, entitled "Collaborative Initial Glaucoma Treatment Study" (CIGTS). This study's purpose is to evaluate whether initial treatment of open angle glaucoma is more effective by means of a stepped, medical regimen or by means of a surgical approach. The Johns Hopkins University's Clinical Center will participate in the CIGTS by identifying and recruiting eligible patients, administering the treatment regimen as assigned by the CIGTS's Coordinating Center and defined within the study's Manual of Operations, following and retaining study patients, recording and transferring study data to the Coordinating Center, and contributing to reports that will present the CIGTS results. This application describes the ability of the Johns Hopkins University Clinical Center to enroll approximately 29 patients per year, based upon pilot studies of patient eligibility conducted during a 3 month period. Details are provided of our plans to identify, recruit, follow, and retain these patients, our intent to obtain consistently high quality data on the visual outcomes of treatment, and the personnel and facilities available within our center to carry out the provisions of the CIGTS's Manual of Operations.