Cognitive Strengths and Weaknesses in Downs syndrome

描述(申请人提供)：对于唐氏综合症(最常见的遗传性智力低下综合征)患者，研究集中在由较差的语言工作记忆和相对较强的视觉空间处理组成的认知特征上。这项研究的意义在于唐氏综合症儿童的教育方式发生了变化。然而，从业者对这些信息的利用相对较少，可能是因为视觉-空间处理的相对强度仍然很少被理解。 在这一应用中，研究者建议：在具体目标1中，描述唐氏综合征视觉空间相对强度的优势和劣势；在特定目标2中，探索视觉空间加工领域的表现与其他加工领域(即言语工作记忆、听觉加工、表达词汇、阅读/解码、逻辑)之间的关系。在随后的研究工作中，研究人员还计划确定通过视觉空间处理的相对优势来改善唐氏综合症患者听觉依赖结果(如语言习得)的策略。

DESCRIPTION (Provided by Applicant): For individuals with Down syndrome, the most common genetic mental retardation syndrome, research is converging on a cognitive profile consisting of poor verbal working memory and relatively stronger visuo-spatial processing. The implications of this research point to changes in the way children with Down syndrome are taught. Yet this information has remained relatively under-utilized by practitioners, possibly because the visuo-spatial processing relative strength remains poorly understood. In this application, the investigator proposes to: in Specific Aim 1, describe the strengths and weaknesses within the visuo-spatial relative strength in Down syndrome; and in Specific Aim 2, explore the relationship between performance on domains within visuo-spatial processing and other domains of processing (i.e. verbal working memory, auditory processing, expressive vocabulary, reading/decoding, logic). In subsequent research endeavors, the investigator also plans to identify strategies for improving auditory-dependent outcomes in Down syndrome (such as language acquisition) through the relative strength in visuo-spatial processing.