The effects of simulated extra-terrestrial conditions on archaeal biology - consequences for space-based bioproduction and planetary colonisation.

由于其对极端环境（盐度、辐射、温度）的耐受性、遗传上的易处理性和对发病机理的低预期性，海蛞蝓是空间和行星生物生产的潜在平台。我们将研究古细菌适应模拟太空飞行和/或火星条件期间发生的变化。这将涉及遗传学、实验进化和深度测序以及微生物生理学和生物化学。

Archaea represent a potential platform for space and planetary bioproduction due to their tolerance of extreme environments (salinity, radiation, temperature), genetic tractability and low expectations of pathogenesis. We will investigate the changes that occur during archaeal adaptation to simulated spaceflight and/or Martian conditions. This will entail genetics, experimental evolution and deep sequencing as well as microbial physiology and biochemistry.