Enhancing barley environmental stress tolerance through targeted mutagenesis.

全球变暖和对季节性降雨变化的预测影响表明，我们可能会看到未来更干燥和更潮湿的生长季节。研究在气候变化的情况下保持产量的育种策略是未来粮食安全的一个关键方面。在植物中，N-末端规则途径被确定为植物对环境胁迫响应的关键生化调节剂。本项目的重点是：1）鉴定谷物中N-末端规则途径的靶蛋白; 2）评估它们在受控环境和田间的影响，以开发具有增强的非生物胁迫耐受性的种质用于植物育种。成功的候选人将与世界上最大的酿酒行业AB InBev，植物和作物科学系以及诺丁汉大学国际酿酒科学中心合作。拟议的实习活动将使学生有机会与百威英博的工作人员互动，学习如何利用基础科学来加强大麦育种。百威英博在美国科罗拉多的柯林斯堡设有全球大麦研究中心、田间试验区和酿造麦芽质量分析实验室设施。此次合作提供了一个机会，使研究培训经验与工业合作伙伴AB InBev的研究需求紧密结合。拟议的就业安排活动将提供可转移技能的培训，以提高学生的就业能力，例如与沿着饲养员一起工作。此外，还将有机会为谷物等商业活动做出贡献，并参观实地实验。这种经验将是对学生的科研培训的宝贵补充，并提供可转移的技能，这将提高他们未来的就业能力。

Global warming and the predicted impact on seasonal rainfall variation suggest that we may see both drier and wetter growing seasons in the future. Research into breeding strategies for maintaining yields in the face of climate change is a key aspect of future food security. In plants, the N-end rule pathway was identified as a key biochemical regulator of plant responses to environmental stress. This project focuses on: 1) identifying target proteins of the N-end rule pathway in cereals; 2) assessing their impact in controlled environments and in the field, in order to develop germplasm with enhanced abiotic stress tolerance for plant breeding. The successful candidate will be working alongside AB InBev, the largest brewing industry in the world, Plant and Crops Sciences Department and the International Centre for Brewing Science at University of Nottingham. The proposed placement activities will give the student the opportunity to interact with AB InBev staff to learn how fundamental science can be used to enhance breeding in barley. AB InBev has a Global Barley Research Centre, field trial areas, and access to the lab facilities for brewing malt quality analysis based, in Fort Collins, Colorado (USA). This collaboration provides an opportunity for research training experience closely aligned to the research needs of the industrial partner, AB InBev. The proposed placement activities will provide training in transferable skills which will enhance the employability of the student such as work along breeders. In addition, there will be opportunities to contribute to commercial events such as Cereals and to visit field experiments. This experience will be a valuable addition to the student's scientific research training and provide transferable skills which will enhance their future employability.