MBRS-SCORE Equipment Supplement Program

描述(由申请人提供)：MBRS-SCORE设备补充计划预计将成为加强汉普顿大学校园生物医学研究的工具。该计划的目标是1)加强研究文化和基础设施，从而增加NIH资助的生物医学项目的数量，2)提高教师的生产力，3)为教师以及少数族裔本科生和研究生提供生物医学培训机会。 加强生物医学仪器核心实验室的基础设施将有助于实现这些目标，方法是扩大汉普顿大学的生物医学研究能力，并为MBRS-SCORE资助的研究人员提供在校园内不容易获得且无法通过传统MBRS-SCORE和“小额赠款”资助机制获得的仪器。该实验室将设在一个专用的共享仪器设施中，将容纳300 MHz核磁共振、LC-MS、密度计、实时热循环仪、高效液相二极管阵列检测器和超速离心机，以及汉普顿大学药学院购买的其他多用户设备。将聘请一名实验室经理来维护和操作核心设备，并培训新的调查人员和未来的MBR分数申请者。对MBRS-SCORE资助的调查人员和关键人员的高级培训将培养一支经验丰富的研究人员队伍，他们可以为新的调查人员和潜在的MBRS-SCORE申请者提供技术援助。预计核心实验室的增加将促进整个校园内生物医学研究人员之间的跨学科项目，并使新的研究人员能够获得成功竞争MBRS-SCORE和RO1资助机制所需的初步数据。

DESCRIPTION (provided by applicant): The MBRS-SCORE Equipment Supplement Program is predicted to be the vehicle by which biomedical research on the campus of Hampton University is enhanced. The goals of this program are 1) to enhance research culture and infrastructure, and thereby increase the numbers of NIH-funded biomedical projects, 2) to increase faculty productivity and 3) to provide biomedical training opportunities to faculty as well as minority undergraduate and graduate students. The infrastructure enhancement of a Biomedical Instrumentation Core Laboratory will facilitate the realization of these goals by expanding the biomedical research capabilities of Hampton University and by providing MBRS-SCORE funded researchers with access to instrumentation that are not readily available on campus and are unattainable through conventional MBRS-SCORE and "small grant" funding mechanisms. The laboratory will be located in a dedicated shared instrument facility and will house a 300 MHz NMR, LC-MS, densitometer, real time thermal cycler, HPLC-diode array detector, and an ultracentrifuge, along with other multi-user equipment purchased by the Hampton University School of Pharmacy. A laboratory manager will be hired to maintain and operate the core equipment as well as train new investigators and prospective MBRS-SCORE applicants. Advanced training of MBRS-SCORE funded investigators and key personnel will create a cadre of experienced researchers who can lend technical assistance to new investigators and prospective MBRS-SCORE applicants. It is anticipated that the addition of the core laboratory will foster interdisciplinary projects among biomedical researchers across the campus and also enable new investigators to obtain preliminary data required to successfully compete for MBRS-SCORE and RO1 funding mechanisms.