The Mouse as a Tool for Ear Research

描述（由申请人提供）：本申请为2003年9月21日至23日在缅因州巴尔港杰克逊实验室（TJL）举行的“鼠标作为耳朵研究工具”会议提供为期一年的支持。我们目前正处于一场遗传学革命之中，这场革命有望将“突破性”生物医学研究推向新的水平。这场革命的很大一部分取决于对基因之间关系及其对复杂生物系统和表型的影响的分析。研究人员必须越来越熟练地应用遗传模型来解决各种重要的生物学问题。本次会议的目的是为在视听神经生物学领域工作的研究人员和学生提供一个论坛。在过去，老鼠并不是研究听觉系统的主要实验动物。因此，“老鼠作为耳朵研究的工具”被设计成一个论坛，在这个论坛上，研究非老鼠模型的研究人员和学生可以研究实验室老鼠的巨大潜力。此外，使用老鼠的研究人员将能够从该领域的其他专家那里扩展他们的技术知识。这个为期两天的会议是围绕四个一小时的教程安排的。简短的演讲将详细介绍教程中展示的技术，并提供前沿研究的例子。大多数报告将是由组织者邀请的论文，但也有时间提供贡献论文和简短的摘要演讲。最终，这次会议将把学生和具有不同专业知识和经验的知名研究者聚集在一起讨论他们的研究成果，确定共同研究兴趣的领域，并制定未来的方向。

DESCRIPTION (provided by applicant): This application is for one year of support for the meeting "The Mouse as a Tool for Ear Research" to be held at The Jackson Laboratory (TJL) in Bar Harbor Maine on September 21-23, 2003. We are currently in the midst of a genetics revolution that promises to push "breakthrough" biomedical research to new levels. A large part of this revolution depends upon the analysis of the relationships between genes and their effects on complex biological systems and phenotypes. Investigators must become increasingly skilled in the application of genetic models to address a variety of important biological questions. The objective of this meeting is to provide a forum for researchers and students who work in areas of audio-sensory neurobiology. In the past the mouse has not been a major experimental animal for studying the auditory system. "The Mouse as a Tool for Ear Research'" is therefore designed as a forum in which researchers and students studying non-murine models can investigate the enormous potential of the laboratory mouse. In addition, researchers using the mouse will be able to expand their knowledge of techniques from other experts in the field. This two-day meeting is arranged around four one-hour tutorials. Short presentations will elaborate on techniques demonstrated in the tutorials and provide examples of cutting edge research. Most presentations will be invited papers by the organizers but there are times available for contributed papers and short abstract talks. Ultimately, this meeting will bring students and established investigators with varying expertise and experience together to discuss their research findings, identify areas of common research interest and develop future directions.