UICC Intl Conference on Familial Cancer--US Support

描述(由申请者提供)：我们请求部分支持将于2003年6月4日至6日在俄克拉何马州俄克拉何马城举行的UICC家族性癌症国际会议：生物学和临床护理。本次研究会议将把资深和初级研究人员聚集在一起，总结通过临床研究、(ECO)遗传流行病学以及癌症风险评估、咨询和基因测试来理解和控制家族性癌症的进展。主题包括：特定部位的家族性癌症(乳腺癌、卵巢癌、结肠癌、胰腺癌、胃癌、黑色素瘤)和癌症家族综合征的特征；发病率综合征和易患癌症的主要基因的特征；多个修饰基因和基因-环境相互作用的确定；风险评估、遗传咨询和通过筛查、手术和化学预防对癌症高危人群进行管理的临床实践；跨学科方法的进展，包括实验室、遗传流行病学技术、生物信息学和系统生物学；种族、文化和国际相似性和差异；伦理、法律、社会和心理影响；以及未来的研究和临床建议。其目标是促进来自美国和海外的遗传学家、肿瘤学家和流行病学家之间更大的研究合作和协作，以通过家庭研究的跨学科战略解决人类肿瘤问题。本次会议的创新之处在于其网站、摘要的出版和为遗传学、流行病学和肿瘤学的研究受训人员提供的整笔旅费补助。 国际抗癌联盟(UICC)是一个国际非政府组织，它联合了来自世界各地的自愿癌症协会，包括美国癌症协会。作为其流行病学计划的一部分，UICC于1991年启动了家族性癌症和预防项目，并在日本和中国举行了两次重要会议。现在，UICC项目的组织者第一次要求在北美，特别是俄克拉何马州举办会议。俄克拉何马城儿童医学研究所和俄克拉荷马大学健康科学中心的联合赞助是安全的，但NIH的支持对于支持美国参与的某些方面是必不可少的，包括某些会议后勤、主旨演讲者和奖学金，这些奖学金将竞争性地授予肿瘤学、医学遗传学、遗传咨询和遗传流行病学的少数族裔、女性和受训人员。

DESCRIPTION (provided by applicant): We request partial support for a UICC International Conference on Familial Cancer: Biology and Clinical Care, to be held in Oklahoma City, Oklahoma, on June 4-6, 2003. This research meeting will bring senior and junior researchers together to summarize progress in understanding and controlling familial cancer via clinical research, (eco)genetic epidemiology, and cancer risk assessment, counseling, and gene testing. Topics include: site-specific familial cancers (breast, ovary, colon, pancreas, stomach, melanoma) and cancer family syndromes; characterization of rate syndromes and major genes that predispose to cancer; identification of multiple modifying genes and gene-environmental interactions; clinical practice of risk assessment, genetic counseling, and management of high risk persons for cancer by screening, surgery, and chemoprevention; advances in interdisciplinary methods, including laboratory, genetic epidemiologic techniques, bioinformatics, and systems biology; ethnic, cultural, and international similarities and differences; ethical, legal, social, and psychological implications; and future research and clinical recommendations. The goal is to stimulate greater research cooperation and collaboration among geneticists, oncologists, and epidemiologists from the US and abroad to address the problem of human neoplasia via the interdisciplinary strategy of family studies. Innovative aspects of this Conference are its website publication of abstracts and block travel grant for research trainees in genetics epidemiology and oncology. The International Union Against Cancer (UICC) is the international nongovernmental organization that unites voluntary cancer societies from around the world, including the American Cancer Society. As part of its Epidemiology Program, the UICC started a Familial Cancer and Prevention Project in 1991 and held two major meetings, in Japan and China. Now, for the first time, organizers of the UICC Project have asked that the Conference be mounted in North America, specifically Oklahoma. Co-sponsorship by the Children's Medical Research Institute of Oklahoma City and the University of Oklahoma Health Sciences Center is secured, but NIH support is essential to support certain aspects of US participation, including certain conference logistics, keynote speakers, and scholarships to be awarded competitively for minorities, women, and trainees in oncology, medical genetics, genetic counseling, and genetic epidemiology.