MASTERS PROGRAM IN PATIENT-ORIENTED RESEARCH

本申请要求资助一个为期两年的，教学硕士课程，以病人为导向的研究，正在开发的内科医生和外科医生（P和S）和公共卫生学院（SPH）的哥伦比亚大学。 该计划将由医学教授、GCRC项目主任、哥伦比亚欧文临床研究中心主任亨利金斯伯格和生物统计学临床研究方法硕士学位课程副教授兼主任梅丽莎贝格领导。 该提案的目标是开发一个强大的，多学科的教学培训计划，将准备作为临床科学家的独立职业的年轻研究者。 具体目标是：（1）开发一个以病人为导向的研究课程，导致公共卫生学院的硕士学位，这将为年轻的研究人员开始他们的职业生涯在临床研究提供一个广泛的基础。(2)组建一个由活跃的临床研究科学家组成的咨询委员会，该委员会将建立和应用年轻研究人员作为硕士课程学位候选人的选择和评估指南。(3)启动并保持一个长期的后续计划，以确定硕士课程对职业发展的影响。 一个咨询委员会已从P和S，SPH，牙科和口腔外科学院，和护理学院的高级临床研究人员。 课程将集中在生物统计学和流行病学，但将包括药理学，实验室方法，负责任的研究和资助机会的行为必修课程。 将有一个持续的研究座谈会，其中将包括药物开发，FDA的要求和专利问题的研讨会系列。 所有学位候选人将写一个NIH式的补助金，将由生物统计学司的成员赞助，并由来自各部门和学校的高级研究人员指导整个校园。 哥伦比亚大学及其主要附属机构圣卢克斯罗斯福医院中心和哈莱姆医院中心的博士后研究员、讲师和助理教授的潜在申请者人数众多，才华横溢，许多NIH资助的培训赠款和K奖已经到位。 妇女和少数民族在申请人中的代表性很高。 公共卫生学院，内科医生和外科医生学院以及长老会医院对拟议的计划做出了杰出的承诺，承诺每年支持12名学生获得全额学费奖学金：这将确保每年都有优秀的申请人。

This application requests funding for a two-year, didactic Master's Program in Patient-Oriented Research that is being developed jointly by the College of Physicians and Surgeons (P and S) and the School of Public Health (SPH) of Columbia University. The program will be led by Henry Ginsberg, Professor of Medicine, Program Director of the GCRC, and Director of the Irving Center for Clinical Research at Columbia, and Melissa Begg, Associate Professor and Director of the Master's degree track in Clinical Research Methods in Biostatistics. The goal of this proposal is to develop a strong, multidisciplinary didactic training program that will prepare young investigators for independent careers as clinical scientists. The Specific Aims are: (1)To develop a curriculum in Patient-Oriented Research, leading to a Master's degree from the School of Public Health, that will provide a broad foundation for young investigators beginning their careers in clinical investigation. (2) To assemble an Advisory Board of active clinical research scientists that will establish and apply guidelines for the selection and evaluation of young investigators as degree candidates in the Master's program. (3) To initiate and maintain a long-term follow-up program to determine the impact of the Master's program on career development. An Advisory Board has been drawn from senior clinical investigators at P and S, SPH, the School of Dental and Oral Surgery, and the School of Nursing. The curriculum will be centered upon biostatistics and epidemiology, but will include required courses in pharmacology, laboratory methods, the responsible conduct of research and funding opportunities. There will be a continuing series of research colloquia which will include seminars on drug development, FDA requirements and patent issues. All degree candidates will write an NIH-style grant that will be sponsored by a member of the Division of Biostatistics and mentored by senior investigators from departments and schools Campus-wide. The potential applicant pool of postdoctoral fellows, Instructors, and Assistant Professors at Columbia and its major affiliates, the St. Lukes Roosevelt Hospital Center and the Harlem Hospital Center, is large and talented, with many NIH-funded training grants and K awards already in place. Women and minorities are very well represented in the applicant pool. The School of Public Health, the College of Physicians and Surgeons, and the Presbyterian Hospital have made an outstanding commitment to the proposed program by pledging to support twelve students each year with full tuition scholarships: this will ensure an outstanding applicant pool each year.