CANCER CENTER SUPPORT GRANT (CCSG)

本申请为爱荷华大学癌症中心（UICC）申请癌症中心支持基金。爱荷华大学医学院和爱荷华大学医院和诊所是爱荷华州指定的三级保健医疗中心。爱荷华大学癌症中心成立于1980年，旨在协调爱荷华大学的癌症相关研究、临床和教育活动。最近对UICC的额外机构支持加强了该中心在指导和协调大学内所有癌症研究活动方面的作用。这些承诺包括目前的UICC临床设施，用于UICC的住院、门诊、临床研究和行政活动，以及一座新的癌症研究大楼，将为UICC的研究人员提供超过30,000平方英尺的实验室空间。校务中心在行政上是一个矩阵中心，有来自全校6个学院27个系的123名成员。UICC的成员每年有26,184,734美元用于癌症相关的外部研究。中心下设6个研究方向：1)癌症流行病学；2)肿瘤细胞活化；3)实验治疗学；4)自由基与细胞膜；5)分子与肿瘤病毒学；6)转移分子机制。此外，UICC还支持四个共享资源，包括1)流式细胞术，2)组织培养/杂交瘤，3)生物统计学和4)临床试验支持。通过这些项目和核心，UICC加强了互动，支持合作和临床试验支持。通过这些项目和核心，UICC加强了相互作用，支持合作，并确定了未来癌症研究活动的方向。UICC的其他活动包括严格的规划和评估过程，以及为UICC成员提供的各种试点资助项目，旨在支持新的研究人员并鼓励发展新的合作。

This application requests Cancer Center Support Grant funding for The University of Iowa Cancer Center (UICC). The UICC is based in the University of Iowa College of Medicine and the University of Iowa Hospitals and Clinics which is the designated tertiary care medical center for the state of Iowa. The University of Iowa Cancer Center was established in 1980 to coordinate the cancer-related research, clinical and educational activities of the University of Iowa. Recent additional institutional support to the UICC has strengthened the role of the Center in directing and coordinating all cancer research activities within the University. Among these commitments are the current UICC clinical facilities that house the inpatient, outpatient, clinical research and administrative activities of the UICC, and a new cancer research building that will supply over 30,000 square feet of laboratory space for UICC investigators. The UICC functions administratively as a matrix center with 123 members from six colleges and 27 departments across the University. The members of the UICC have $26,184,734 of cancer- related external research support annually. The UICC is organized into six research programs including 1) Cancer Epidemiology, 2) Cellular Activation in Cancer, 3) Experimental Therapeutics, 4) Free Radicals and Membranes, 5) Molecular and Tumor Virology, and 6) Molecular Mechanisms of Metastasis. In addition, the UICC supports four shared resources including 1) Flow Cytometry, 2) Tissue Culture/Hybridoma, 3) Biostatistics and 4) Clinical Trials Support. Through these programs and cores, the UICC enhances interactions, supports collaborations, and 4) Clinical Trials Support. Through these programs and cores, the UICC enhances interactions, support collaborations, and sets the direction of future cancer research activities. Additional UICC activities include a rigorous planning and evaluation process and a variety of pilot grant programs for UICC members designed to support new investigators and encourage development of new collaborations.