VOCABULARY MANAGEMENT FOR CLINICAL RESEARCH DATABASES

建议书(改编自申请人的摘要)：本申请书提供一份 医学信息学领域的职业发展规划，跨越临床 试验、计算机科学和医学。这样做的长期目标是 提交意见书是启动一项独立研究计划，旨在确定 用于计算机化的通用数据项的组织和结构模型 临床研究数据的测量。这项研究的总体目标是 帮助标准化临床试验数据，从而改善以患者为中心 研究并增加研究成果向临床实践的转化。 在完成预防医学的临床培训后，应聘者 参加了为期两年的医学信息学博士后奖学金。 在此期间，应聘者获得了计算机方面的经验和专业知识 科学和临床计算研究问题，如临床数据库 开发和设计。自2000年7月1日起，候选人将成为 基督教青年会助理教授。这个职业奖项将提供无价的 支持候选人继续发展相关领域的专门知识 计算机科学和以患者为中心的健康服务研究，并 作为初级教员实现科学独立的直接目标 成员。 一批优秀的导师和顾问已经聚集在一起，他们将 就候选人的研究方向提供指导，并 长期的职业目标，并提供关于道德行为的建议和建议 研究的成果。职业发展计划包括额外培训，以 包括计算机科学领域的课程作业和密集研讨会， 调查医学和高级卫生服务研究。 研究计划包括：1)建立先进的信息学 用于搜索和组织临床内部数据词典的工具 研究数据库(Trial/DB)和整合标准化临床 将词汇表转换为试用/数据库；2)开发允许相关数据项的模型 以有组织的方式保持，从而促进未来的合作和 共享；以及3)与目前使用 Trial/DB用于测试、改进和改进上述在 正在进行的研究或新研究的背景。

PROPOSAL (Adapted from the applicant's abstract): This application presents a career development plan in the field of Medical Informatics, spanning clinical trials, computer science and medicine. The long-term objective of this submission is to launch an independent research program aimed at identifying models of organizing and structuring generic data items for computerized measurements of clinical research data. The overall goal of this research is to help standardize clinical trials data, thereby improving patient-oriented research and increasing the translation of research into clinical practice. After completing clinical training in preventive medicine, the candidate participated in a two-year postdoctoral fellowship in Medical Informatics. During this time, the candidate gained experience and expertise in computer science and clinical computing research issues such as clinical database development and design. As of July 1, 2000, the candidate will become an Assistant Professor in the YCMI. This career award will provide invaluable support for the candidate to continue to develop expertise in relevant areas of computer science and patient-oriented health services research, and to achieve the immediate goal of scientific independence as a junior faculty member. An outstanding group of mentors and advisors have been assembled who will provide guidance with respect to the direction of the candidate's research and long-term career goals, and provide advice and counsel on the ethical conduct of research. The career development plan includes additional training to include coursework and intensive workshops in the areas of computer science, investigative medicine, and advanced health services research. The research plan presented below involves: 1) building advanced informatics tools for searching and organizing the internal data dictionary of a clinical research database (Trial/DB) and integrating standardized clinical vocabularies into Trial/DB; 2) developing models that allow related data items to be maintained in organized ways, thus promoting future collaboration and sharing; and 3) collaborating with clinical investigators currently using Trial/DB to test, refine, and improve the tools and models developed above in the context of ongoing or new studies.