Physiology of Cumulative Low Back Disorders

描述：与关节脱位相关的生物力学和生理过程 长期应用安慰剂引起的累积性脊柱疾病 将对脊柱的静态和重复性职业负荷进行调查。它 假设脊柱组织在暴露于蠕变/伸长时，由于 重复或静态负荷，导致体内感官感受器脱敏 以及随之而来的反射性肌肉活动的丧失，使脊柱裸露 到不稳定和潜在的伤害。蠕变/伸长率完全恢复 而在连续工作期间休息时的肌肉活动可能不会 允许累积增加残余蠕变/伸长率 是时候发展出持久的神经肌肉疾病了。 由体内猫科动物组成的五年实验研究计划 模型将系统地探索累积载荷之间的关系 用于脊柱韧带、关节盘等，按顺序进行静态和循环运动 /休息时间以及在8小时的休息时间内恢复到 椎旁肌的活动水平及其功能障碍。 这项研究的结果将为生物力学和 常见职业活动中腰背疾患的神经生理学； 深入了解顺序累积负荷和每日休息的影响 关于脊柱疾患的近期和远期发展；并描绘 最佳工作/休息时间，可最大限度地减少或防止低血压的发展 背部疾患是最常见的职业活动。

DESCRIPTION: The biomechanical and physiological processes associated with the development of cumulative spinal disorders due to long term application of static and repetitive occupational loads to the spine will be investigated. It is hypothesized that spinal tissues, when exposed to creep / elongation due to repetitive or static loads, cause desensitization of sensory receptors within and consequent loss of reflexive muscular activity, rendering the spine exposed to instability and potential injury. Full recovery of the creep / elongation and muscle activity while resting between sequential work periods may not be possible, allowing the cumulative increase of residual creep / elongation over time to develop long lasting neuromuscular disorders. A five year experimental research program consisting of the in-vivo feline model will systematically explore the relationship between cumulative loads applied to spinal ligaments, discs, etc., in sequential static and cyclic work / rest periods as well as the following recovery in eight hours of rest to the activity level of paraspinal muscles and the disorders in their functions. The results of this research will provide strong insights into biomechanics and the neurophysiology of low back disorders in common occupational activities; provide an insight to the effect of sequential cumulative loads and daily rest on development of spinal disorder in the short and long term; and delineate optimal work / rest periods that may minimize or prevent the development of low back disorders in the most common occupational activities.