Neural Mechanisms in Casdiovascular Regulation

描述(由申请人提供)： “心血管调节中的神经机制”会议是一个长期的FASE B夏季研究会议，此前曾在1982年、1984年、1987年、1990年、1994年、1996年、1999年和2002年举行。以前的会议都有很多人参加，它们的价值得到了该领域主要调查人员的认可。这一课题被广泛认为是一个重要的研究领域。神经系统在动脉血压的调节、心肾功能的调节、晕厥、心律失常、猝死等病理状态的发生中起重要作用。对基础神经机制感兴趣的基础科学家、综合生理学家和对疾病中心血管调节失调机制感兴趣的临床研究人员都对该领域感兴趣。这份关于2004年FASE B夏季会议的提案将侧重于了解心血管系统对来自外部和内部环境的挑战的生理和病理反应所涉及的中心机制。正如1932年沃尔特·B·坎农在《身体的智慧》中所阐述的那样，系统适应环境挑战和维持动态平衡的能力是维持生命的基础。2004年FASEB“心血管调节中的神经机制”夏季会议的科学会议在副标题“健康和疾病中的环境挑战和心血管调节”下联系在一起。每堂课将涵盖特定的外部或内部环境挑战，以及参与调节心血管功能的神经机制的反应。每一次会议的演讲者将涉及每个主题，从确定对人类健康的挑战到了解所涉及的分子和细胞机制。大约160名与会者将从感兴趣的申请者中挑选出来。会议将包括4个全体会议，每个会议由2-3个报告组成，延长的讨论会议和海报报告。全体会议包括：1)渗透挑战和体液调节；2)类固醇激素挑战和心血管功能的中枢调节；3)呼吸挑战和循环的神经控制；以及4)运动训练、温度应激和循环的神经控制。大多数受邀发言者已同意参加，将鼓励年轻调查人员参加。将分配时间进行非正式讨论和社会互动。来自美国和其他国家的科学家、年轻的研究人员和女性在该项目中都有很好的代表。

DESCRIPTION (provided by applicant): The conference "Neural Mechanisms in Cardiovascular Regulation" is a long-running FASEB Summer Research Conference previously held in 1982, 1984, 1987, 1990, 1994, 1996, 1999 and 2002. The previous conferences have been well attended and their value recognized by leading investigators in the field. The topic is widely recognized as an important area of research. The nervous system plays a major role in regulation of arterial pressure, modulation of cardiac and renal function, and occurrence of syncope, cardiac arrhythmias and sudden death in pathologic states. The field is of interest to basic scientists interested in fundamental neural mechanisms, integrative physiologists, and clinical investigators interested in mechanisms of cardiovascular dysregulation in disease. This proposal for the FASEB Summer Conference 2004 will focus on understanding the central mechanisms involved in the physiological and pathological responses of the cardiovascular system to challenges from the external and internal environment. As articulated in 1932 by Walter B. Cannon in "The Wisdom of the Body", the ability of systems to adapt to environmental challenges and maintain homeostasis is fundamental to sustaining life. The scientific sessions for the 2004 FASEB "Neural Mechanisms in Cardiovascular Regulation" Summer Conference are tied together under the subtitle Environmental Challenges and Cardiovascular Regulation in Health and Disease. Each session will cover a specific external or internal environmental challenges and the responses of the neural mechanisms that are engaged to regulate cardiovascular function. Speakers for each session will span each topic from the identification of the challenge to human health to the understanding of the molecular and cellular mechanisms involved. Approximately 160 conference attendees will be selected from interested applicants. The conference will include 4 plenary sessions consisting of 2-3 presentations each, extended discussion sessions, and poster presentations. The plenary sessions include: 1) Osmotic Challenge and Body Fluid Regulation; 2) Steroid Hormone Challenges and Central Regulation of Cardiovascular Function; 3) Respiratory Challenges and Neural Control of the Circulation; and 4) Exercise Training, Temperature Stress and Neural Control of the Circulation. The majority of invited speakers have already agreed to participate and participation of young investigators will be encouraged. Time will be allotted for informal discussions and social interaction. Scientists from the United States and other countries, young investigators, and women are well represented in the program.